Gene Symbol | NMUR1 |
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Entrez Gene | 10316 |
Alt Symbol | (FM-3), FM-3, FM3, GPC-R, GPR66, NMU1R |
Species | Human |
Gene Type | protein-coding |
Description | neuromedin U receptor 1 |
Other Description | G protein-coupled receptor 66|G-protein coupled receptor 66|G-protein coupled receptor FM-3|NMU-R1|neuromedin-U receptor 1 |
Swissprots | Q8NE20 Q7LDP6 O43664 Q9HB89 |
Accessions | AAC02680 AAY24249 EAW70966 Q9HB89 AF272362 AAG24793 AK300222 BAG61990 AK301102 BAG62701 BC036543 AAH36543 BC051914 AAH51914 BP198644 XM_006712195 XP_006712258 XM_006712196 XP_006712259 XM_011510487 XP_011508789 XM_011510488 XP_011508790 XM_011510489 XP_011508791 NM_006056 NP_006047 |
Function | Receptor for the neuromedin-U and neuromedin-S neuropeptides. {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. {ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:9782091}. |
Top Pathways | Neuroactive ligand-receptor interaction |
NMUR1 (C-18) - sc-47241 from Santa Cruz Biotechnology
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NMUR1 (H-45) - sc-135159 from Santa Cruz Biotechnology
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NMUR1 (M-53) - sc-135160 from Santa Cruz Biotechnology
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Anti-NMUR1 antibody - ab126961 from Abcam
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Anti-NMUR1 antibody - ab121959 from Abcam
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Anti-NMUR1 Antibody - LS-C155415 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (N-Terminus) - LS-C16906 from LifeSpan Bioscience
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Anti-NMUR1 Antibody - LS-C16907 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (N-Terminus) - LS-C16909 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (aa1-50) - LS-C120756 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (C-Terminus) IHC-plus⢠- LS-A397 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A396 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (aa255-304) - LS-C151889 from LifeSpan Bioscience
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Anti-NMUR1 Antibody (C-Terminus) - LS-C151888 from LifeSpan Bioscience
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Neuromedin U R1/NMUR1 Antibody - NBP2-19556 from Novus Biologicals
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Neuromedin U R1/NMUR1 Antibody - NBP1-83433 from Novus Biologicals
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Neuromedin U R1/NMUR1 Antibody - NLS397 from Novus Biologicals
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Neuromedin U R1/NMUR1 Antibody - NLS396 from Novus Biologicals
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Neuromedin U R1/NMUR1 Antibody - H00010316-A01 from Novus Biologicals
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NMUR1/GPR66 Polyclonal Antibody - bs-11420R from Bioss
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NMUR1/GPR66 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11420R-A350 from Bioss
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NMUR1/GPR66 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11420R-A488 from Bioss
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NMUR1/GPR66 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11420R-A555 from Bioss
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NMUR1/GPR66 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11420R-A647 from Bioss
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NMUR1/GPR66 Polyclonal Antibody, Cy3 Conjugated - bs-11420R-Cy3 from Bioss
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