Gene Symbol | NMUR1 |
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Entrez Gene | 10316 |
Alt Symbol | (FM-3), FM-3, FM3, GPC-R, GPR66, NMU1R |
Species | Human |
Gene Type | protein-coding |
Description | neuromedin U receptor 1 |
Other Description | G protein-coupled receptor 66|G-protein coupled receptor 66|G-protein coupled receptor FM-3|NMU-R1|neuromedin-U receptor 1 |
Swissprots | Q8NE20 Q7LDP6 O43664 Q9HB89 |
Accessions | AAC02680 AAY24249 EAW70966 Q9HB89 AF272362 AAG24793 AK300222 BAG61990 AK301102 BAG62701 BC036543 AAH36543 BC051914 AAH51914 BP198644 XM_006712195 XP_006712258 XM_006712196 XP_006712259 XM_011510487 XP_011508789 XM_011510488 XP_011508790 XM_011510489 XP_011508791 NM_006056 NP_006047 |
Function | Receptor for the neuromedin-U and neuromedin-S neuropeptides. {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. {ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:9782091}. |
Top Pathways | Neuroactive ligand-receptor interaction |
NMUR1 CRISPR/Cas9 KO Plasmid (h) - sc-405595 from Santa Cruz Biotechnology
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NMUR1 HDR Plasmid (h) - sc-405595-HDR from Santa Cruz Biotechnology
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NMUR1 Double Nickase Plasmid (h) - sc-405595-NIC from Santa Cruz Biotechnology
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NMUR1 Double Nickase Plasmid (h2) - sc-405595-NIC-2 from Santa Cruz Biotechnology
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NMUR1 CRISPR Activation Plasmid (h) - sc-405595-ACT from Santa Cruz Biotechnology
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NMUR1 CRISPR Activation Plasmid (h2) - sc-405595-ACT-2 from Santa Cruz Biotechnology
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NMUR1 Lentiviral Activation Particles (h) - sc-405595-LAC from Santa Cruz Biotechnology
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NMUR1 Lentiviral Activation Particles (h2) - sc-405595-LAC-2 from Santa Cruz Biotechnology
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NMUR1 siRNA (h) - sc-61209 from Santa Cruz Biotechnology
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NMUR1 shRNA Plasmid (h) - sc-61209-SH from Santa Cruz Biotechnology
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NMUR1 shRNA (h) Lentiviral Particles - sc-61209-V from Santa Cruz Biotechnology
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Neuromedin U R1/NMUR1 RNAi - H00010316-R02 from Novus Biologicals
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MISSION® esiRNA - EHU002861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15383 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15383 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10524 from Sigma-Aldrich
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NMUR1 siRNA (Human) - CRH6989 from Cohesion Biosciences
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shRNA set against Human NM (NM_006056.4) - SHH353088 from Creative biogene
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NMUR1 shRNA Plasmid (Human) - CHH6989 from Cohesion Biosciences
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NMUR1 miRNA 3'UTR clone - MiUTR4H-TG06057 from Creative biogene
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