| Gene Symbol |
NMUR1
|
| Entrez Gene |
10316
|
| Alt Symbol |
(FM-3), FM-3, FM3, GPC-R, GPR66, NMU1R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuromedin U receptor 1
|
| Other Description |
G protein-coupled receptor 66|G-protein coupled receptor 66|G-protein coupled receptor FM-3|NMU-R1|neuromedin-U receptor 1
|
| Swissprots |
Q8NE20 Q7LDP6 O43664 Q9HB89
|
| Accessions |
AAC02680 AAY24249 EAW70966 Q9HB89 AF272362 AAG24793 AK300222 BAG61990 AK301102 BAG62701 BC036543 AAH36543 BC051914 AAH51914 BP198644 XM_006712195 XP_006712258 XM_006712196 XP_006712259 XM_011510487 XP_011508789 XM_011510488 XP_011508790 XM_011510489 XP_011508791 NM_006056 NP_006047
|
| Function |
Receptor for the neuromedin-U and neuromedin-S neuropeptides. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. {ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:9782091}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: NMUR1 Overexpression Lysate (Adult Normal) [NBP2-07672] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NMUR1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9123_NMUR1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07672-img0001.jpg)