MAP1LC3A

Gene Symbol	MAP1LC3A
Entrez Gene	84557
Alt Symbol	ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
Species	Human
Gene Type	protein-coding
Description	microtubule-associated protein 1 light chain 3 alpha
Other Description	MAP1 light chain 3-like protein 1|MAP1A/1B light chain 3 A|MAP1A/MAP1B LC3 A|MAP1A/MAP1B light chain 3 A|autophagy-related ubiquitin-like modifier LC3 A|microtubule-associated proteins 1A/1B light chain 3|microtubule-associated proteins 1A/1B light chain 3A
Swissprots	Q9BXW5 E1P5P5 E1P5P4 Q9H492
Accessions	EAW76263 EAW76264 EAW76265 EAW76266 Q9H492 AF276658 AAK35151 AL833855 CAD38714 AM392590 CAL37468 BC015810 AAH15810 BM740344 BM919877 BP212418 BT007452 AAP36120 DQ893641 ABM84567 DQ895536 ABM86462 EL954540 H18312 XM_011529083 XP_011527385 XM_011529084 XP_011527386 XM_011529085 XP_011527387 NM_032514 NP_115903 NM_181509 NP_852610
Function	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000269|PubMed:20713600}.
Subcellular Location	Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes.
Tissue Specificity	Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:12740394}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® LC3A siRNA II - 6215 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® LC3A siRNA I - 6214 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

MAP LC3α CRISPR/Cas9 KO Plasmid (h) - sc-400714 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α HDR Plasmid (h) - sc-400714-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α Double Nickase Plasmid (h) - sc-400714-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α Double Nickase Plasmid (h2) - sc-400714-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α CRISPR Activation Plasmid (h) - sc-400714-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α CRISPR Activation Plasmid (h2) - sc-400714-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α Lentiviral Activation Particles (h) - sc-400714-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α Lentiviral Activation Particles (h2) - sc-400714-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α siRNA (h) - sc-106197 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MAP LC3α shRNA Plasmid (h) - sc-106197-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MAP LC3α shRNA (h) Lentiviral Particles - sc-106197-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LC3A RNAi - H00084557-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU088371 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12977 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12977 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04147 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04147

MAP1LC3A siRNA (Human) - CRJ3524 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LC3A RNAi - H00084557-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MAP LC3α CRISPR/Cas9 KO Plasmid (h2) - sc-400714-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP LC3α HDR Plasmid (h2) - sc-400714-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAP1LC3A shRNA Plasmid (Human) - CHJ3524 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MAP1LC3A miRNA 3'UTR clone - MiUTR3H-03977 from Creative biogene Species Reactivities Human

MAP1LC3A miRNA 3'UTR clone - MiUTR3H-03978 from Creative biogene Species Reactivities Human

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