KIAA0101

Gene Symbol KIAA0101
Entrez Gene 9768
Alt Symbol L5, NS5ATP9, OEATC, OEATC-1, OEATC1, PAF, PAF15, p15(PAF), p15/PAF, p15PAF
Species Human
Gene Type protein-coding
Description KIAA0101
Other Description HCV NS5A-transactivated protein 9|PCNA-associated factor|PCNA-associated factor of 15 kDa|hepatitis C virus NS5A-transactivated protein 9|overexpressed in anaplastic thyroid carcinoma 1
Swissprots Q15004 A6NNU5 A8K3Y3 G9G696 G9G694
Accessions AEW89488 AEW89489 AEW89490 AEW89491 AEW89492 AEW89493 AEW89494 AEW89495 AEW89496 AEW89497 AEW89498 AEW89499 AEW89500 AEW89501 AEW89502 AEW89503 AEW89504 AEW89505 AEW89506 AEW89507 AEW89508 AEW89509 AEW89510 AEW89511 AEW89512 AEW89513 AEW89514 AEW89515 AEW89516 AEW89517 AEW89518 AEW89519 AEW89520 AEW89521 AEW89522 AEW89523 AEW89524 AEW89525 AEW89526 AEW89527 AEW89528 AEW89529 AEW89530 AEW89531 AEW89532 AEW89533 AEW89534 AEW89535 AEW89536 AEW89537 AEW89538 AEW89539 AEW89540 AEW89541 AEW89542 AEW89543 AEW89544 AEW89545 AEW89546 AEW89547 AEW89548 AEW89549 AEW89550 AEW89551 AEW89552 AEW89553 AEW89554 AEW89555 AEW89556 AEW89557 AEW89558 AEW89559 AEW89560 AEW89561 AEW89562 AEW89563 AEW89564 AEW89565 AEW89566 AEW89567 AEW89568 AEW89569 AEW89570 AEW89571 AEW89572 AEW89573 AEW89574 AEW89575 AEW89576 AEW89577 AEW89578 AEW89579 AEW89580 AEW89581 AEW89582 AEW89583 AEW89584 AEW89585 AEW89586 AEW89587 AEW89588 AEW89589 AEW89590 AEW89591 AEW89592 AEW89593 AEW89594 AEW89595 AEW89596 AEW89597 EAW77679 EAW77680 EAW77681 Q15004 AF529370 AAQ09604 AK290748 BAF83437 AV757440 AY598324 AAT06735 BC005832 AAH05832 BC007101 AAH07101 BC016782 AAH16782 BF691807 BG502841 D14657 BAA03491 DT220867 HQ447907 ADQ32391 NM_001029989 NP_001025160 NM_014736 NP_055551 NR_109934
Function PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number. {ECO:0000269|PubMed:21673012, ECO:0000269|PubMed:23000965}.
Subcellular Location Nucleus. Cytoplasm, perinuclear region. Note=Following DNA damage, localizes to DNA damage sites. Colocalizes with centrosomes in perinuclear region.
Tissue Specificity Expressed predominantly in liver, pancreas and placenta. Not detected in heart or brain. Highly expressed in a number of tumors, especially esophageal tumors, in anaplastic thyroid carcinomas, adrenocortical carcinomas, and in non-small- cell lung cancer lines. {ECO:0000269|PubMed:11313979, ECO:0000269|PubMed:15789362, ECO:0000269|PubMed:22096502}.

p15 (PAF) (G-11) - sc-390515 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p15 (PAF) (G-11): sc-390515. Western blot analysis of p15 expression in M1 whole cell lysate.

p15 (PAF) (E-16) - sc-65162 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p15 (PAF) (E-16): sc-65162. Western blot analysis of p15 (PAF) expression in mouse thymus tissue extract.

p15 (PAF) (FL-111) - sc-67279 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
p15 (PAF) (FL-111): sc-67279. Western blot analysis of p15 (PAF) expression in U266 whole cell lysate.

p15 (PAF) (K-15) - sc-65163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p15 (PAF) (K-15): sc-65163. Western blot analysis of human recombinant p15 (PAF) fusion protein.

p15 (PAF) (N-14) - sc-55968 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p15 (PAF) (N-14): sc-55968. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing nuclear and cytoplasmic staining of decidual cells.

p15 (PAF) (Q-15) - sc-67923 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p15 (PAF) (Q-15): sc-67923. Western blot analysis of p15 (PAF) expression in mouse thymus tissue extract.

Anti-KIAA0101 antibody - ab56773 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
KIAA0101 antibody (ab56773) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lymph node tissue.

Anti-KIAA0101 antibody - ab126848 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-KIAA0101 antibody - ab108068 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-KIAA0101 antibody (ab108068) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-KIAA0101 antibody - ab172312 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-KIAA0101 antibody (ab172312) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with KIAA0101Lane 2 : Lysate from untransfected 293T cellsLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PCNA-Associated Factor Antibody (aa40-51) - LS-C154792 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PCNA-Associated Factor Antibody (aa8-101) - LS-C178918 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PCNA-Associated Factor Antibody (N-Terminus) - LS-C116915 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIAA0101 antibody LS-C116915 Western blot of HepG2 cell lysate.

Anti-PCNA-Associated Factor Antibody (FITC) - LS-C317502 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCNA-Associated Factor Antibody (Biotin) - LS-C317498 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCNA-Associated Factor Antibody (HRP) - LS-C317503 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KIAA0101 Antibody (aa1-112, Azide-free) - LS-C328163 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-PCNA-Associated Factor Antibody (aa1-50) - LS-C291011 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PAF by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using RIPA buffer from HeLa cells. Antibodies: Affinity purified rabbit anti-PAF antibody used for IP at 6 ug per reaction. PAF was also immunoprecipitated by rabbit anti-PAF antibody BL15806. For blotting immunoprecipitated PAF, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-PCNA-Associated Factor Antibody (aa61-111) - LS-C291010 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PAF by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN or RIPA buffer from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-PAF antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-PCNA-Associated Factor Antibody (clone 3C11-1F11) - LS-C133604 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C11-1F11
Immunoperoxidase of monoclonal antibody to KIAA0101 on formalin-fixed paraffin-embedded human lymph node tissue. [antibody concentration 3 ug/ml].

Anti-PCNA-Associated Factor Antibody IHC-plus™ - LS-B12298 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

PCNA associated factor Antibody (3C11-1F11) - H00009768-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C11-1F11
Western Blot: PCNA associated factor Antibody (3C11-1F11) [H00009768-M01] - Western Blot analysis of KIAA0101 expression in JAR ( Cat # L003V1 ).

PCNA associated factor Antibody - NBP1-80555 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCNA associated factor Antibody [NBP1-80555] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

PCNA associated factor Antibody - NBP2-32112 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCNA associated factor Antibody - NBP2-32117 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCNA associated factor Antibody [NBP2-32117] - Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using RIPA buffer from HeLa cells.  Antibodies:  Affinity purified rabbit anti-PAF antibody NBP2-32117 used for IP at 6 ug per reaction.  PAF was also immunoprecipitated by rabbit anti-PAF antibody NBP2-32117.  For blotting immunoprecipitated PAF, NBP2-32117 was used at 1 ug/ml.  Detection: Chemiluminescence with an exposure time of 3 minutes.
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