Gene Symbol | ASH1L |
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Entrez Gene | 55870 |
Alt Symbol | ASH1, ASH1L1, KMT2H |
Species | Human |
Gene Type | protein-coding |
Description | ash1 (absent, small, or homeotic)-like (Drosophila) |
Other Description | ASH1-like protein|absent small and homeotic disks protein 1 homolog|histone-lysine N-methyltransferase ASH1L|lysine N-methyltransferase 2H|probable histone-lysine N-methyltransferase ASH1L |
Swissprots | Q9P2C7 Q9NR48 Q5T715 Q5T714 Q59GP1 |
Accessions | EAW53068 Q9NR48 AB037841 BAA92658 AB209068 BAD92305 AF257305 AAF68983 AI912552 AK304873 BAG65610 AK307595 BC172595 AAI72595 BQ883186 CN365042 DA236222 XM_005245337 XP_005245394 XM_006711450 XP_006711513 XM_006711451 XP_006711514 XM_006711452 XP_006711515 XM_011509769 XP_011508071 XM_011509770 XP_011508072 NM_018489 NP_060959 |
Function | Histone methyltransferase specifically methylating 'Lys- 36' of histone H3 (H3K36me). {ECO:0000269|PubMed:21239497}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10860993}. Cell junction, tight junction {ECO:0000269|PubMed:10860993}. Chromosome {ECO:0000305|PubMed:10860993}. Note=The relevance of tight junction localization is however unclear. |
Tissue Specificity | Widely expressed, with highest level in brain, heart and kidney. {ECO:0000269|PubMed:10860993}. |
Top Pathways | Tight junction, Lysine degradation |
Human KMT2H / ASH1 protein fragment - ab163261 from Abcam
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Human KMT2H / ASH1 protein fragment - ab195166 from Abcam
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Recombinant Human ASH1 Protein - H00055870-Q01 from Novus Biologicals
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ASH1L - H00055870-Q01-10 from Acris Antibodies
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ASH1L - H00055870-Q01-25 from Acris Antibodies
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Recombinant ASH1L (2407-2579) protein - 31445 from ActiveMotif
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Recombinant Human ATAD2, His&FLAG-tagged - ASH1L-30H from Creative Biomart
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Recombinant Human Histone-lysine N-methyltransferase ASH1L(ASH1L) ,partial - CSB-YP865114HU CSB-EP865114HU CSB-BP865114HU CSB-MP865114HU from Cusabio
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ASH1, Peptide - MBS657942 from MyBioSource
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ASH1, Peptide - MBS658751 from MyBioSource
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Recombinant Human ASH1L protein, GST-tagged - ASH1L-47H from Creative Biomart
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Recombinant Human ASH1L protein, His-tagged - ASH1L-48H from Creative Biomart
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Recombinant Human ASH1L protein, GST-tagged - ASH1L-49H from Creative Biomart
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Recombinant Human ASH1L protein, His-tagged - ASH1L-50H from Creative Biomart
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ASH1 Protein - NBP1-90083PEP from Novus Biologicals
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ASH1L Peptide, Human - M34GP01039H from Creative Peptides
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Histone-lysine N-methyltransferase ASH1L (ASH1L), partial, Recombinant Protein - MBS1394904 from MyBioSource
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