MMRN1

Gene Symbol	MMRN1
Entrez Gene	22915
Alt Symbol	ECM, EMILIN4, GPIa*, MMRN
Species	Human
Gene Type	protein-coding
Description	multimerin 1
Other Description	EMILIN-4\|elastin microfibril interface located protein 4\|elastin microfibril interfacer 4\|endothelial cell multimerin\|glycoprotein Ia*\|multimerin-1
Swissprots	Q4W5L1 Q6ZUL9 Q6P3T8 Q13201
Accessions	AAY40957 EAX06037 EAX06038 Q13201 AK125557 BAC86201 AK302421 BAH13704 AK313566 BAG36340 BC063848 AAH63848 BM126740 HQ258009 ADR82763 U27109 AAC52065 XM_005262856 XP_005262913 NM_007351 NP_031377
Function	Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein. {ECO:0000269\|PubMed:16363244, ECO:0000269\|PubMed:19132231, ECO:0000269\|PubMed:7629143}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Synthesized by endothelial cells and megakaryocytes. Stored in platelet alpha granules and endothelial cell Weibel-Palade bodies, following activation of these cells, it is released and attached to megakaryocytes, platelets, endothelium and subendothelium of blood vessels. Not found in plasma. Found in vascular tissues such as placenta, lung, and liver. {ECO:0000269\|PubMed:7629143, ECO:0000269\|PubMed:8514871}.

Multimerin-1 (H-6) - sc-398941 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Multimerin-1 (H-6): sc-398941. Western blot analysis of Multimerin-1 expression in human platelet extract.

Multimerin-1 (E-18) - sc-104426 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Multimerin-1 (E-18): sc-104426. Western blot analysis of Multimerin-1 expression in U-251-MG whole cell lysate (A) and human liver tissue extract (B).

Multimerin-1 (H-178) - sc-367225 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Multimerin-1 (N-17) - sc-104427 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Multimerin-1 (N-17): sc-104427. Western blot analysis of Multimerin-1 expression in non-transfected: sc-117752 (A) and human Multimerin-1 transfected: sc-373115 (B) 293T whole cell lysates.

Multimerin-1 (S-14) - sc-104428 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Multimerin-1 (S-14): sc-104428. Western blot analysis of Multimerin-1 expression in HUV-EC-C whole cell lysate.

Anti-MMRN1 antibody - ab130585 from Abcam

Prices	$376.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 antibody (ab130585) at 1/100 dilution + WiDr cell line lysates at 35 µg

Anti-MMRN1 antibody - ab56890 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab56890 MMRN1 antibody at 1ug/ml.

Anti-MMRN1 Antibody (aa179-207, APC) - LS-C223297 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa179-207, AP) - LS-C223296 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa179-207, FITC) - LS-C223299 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa179-207, Biotin) - LS-C223298 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa179-207, PE) - LS-C223301 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa179-207, Azide-free, HRP) - LS-C223302 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa846-1084, Biotin) - LS-C301285 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa807-1053, Biotin) - LS-C300166 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa807-1053, FITC) - LS-C304468 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa846-1084, FITC) - LS-C304619 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa178-207) - LS-C323051 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (clone 1G10) - LS-C139477 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1G10

Detection limit for recombinant GST tagged MMRN1 is 1 ng/ml as a capture antibody.

Anti-MMRN1 Antibody (aa807-1053) - LS-C295458 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody (aa846-1084) - LS-C295459 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MMRN1 Antibody - LS-C334855 from LifeSpan Bioscience

Prices	$255.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence analysis of U2OS cell using MMRN1 antibody. Blue: DAPI for nuclear staining.

Anti-MMRN1 Antibody (aa179-207) - LS-C164252 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Western blot of lysates from HLVEC, HUVEC cell line (from left to right), using MMRN1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

MMRN1 Antibody - NBP1-84014 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

MMRN1 Antibody (4B9) - H00022915-M02 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4B9

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