TRIM9

Gene Symbol	TRIM9
Entrez Gene	114088
Alt Symbol	RNF91, SPRING
Species	Human
Gene Type	protein-coding
Description	tripartite motif containing 9
Other Description	E3 ubiquitin-protein ligase TRIM9|RING finger protein 91|homolog of rat RING finger Spring|tripartite motif-containing 9|tripartite motif-containing protein 9
Swissprots	Q9C027 D3DSB7 Q96D24 Q9C025 Q92557 Q96NI4 D3DSB8 Q9C026
Accessions	EAW65680 EAW65681 EAW65682 EAW65683 EAW65684 Q9C026 AK054781 AK055388 BAB70913 BC013414 AAH13414 BC063872 AAH63872 BF966522 D87458 BAA13398 DA101991 DA173440 T77638 XM_005267301 XP_005267358 XM_005267302 XP_005267359 XM_006720018 XP_006720081 XM_011536389 XP_011534691 XM_011536390 XP_011534692 XM_011536391 XP_011534693 XM_011536392 XP_011534694 NM_015163 NP_055978 NM_052978 NP_443210
Function	E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. {ECO:0000269|PubMed:20085810}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20085810}. Cell projection, dendrite {ECO:0000269|PubMed:20085810}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle- associated form. Associated with the cytoskeleton (By similarity). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum. {ECO:0000250}.
Tissue Specificity	Brain. Highly expressed in the cerebral cortex (at protein level). Severely decreased in the affected brain areas in Parkinson disease and dementia with Lewy bodies. {ECO:0000269|PubMed:20085810}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TRIM9 (N-15) - sc-107102 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

TRIM9 (S-12) - sc-107103 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

TRIM9 (H-24) - sc-134124 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Rabbit Clonality Polyclonal

TRIM9 (H-40) - sc-368106 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-TRIM9 antibody - ab101856 from Abcam Host Rabbit Clonality Polyclonal

Anti-TRIM9 antibody - ab173447 from Abcam Prices $370.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-TRIM9 antibody - ab82654 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TRIM9 antibody - ab82675 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TRIM9 antibody - ab28463 from Abcam Host Rabbit Clonality Polyclonal

Anti-TRIM9 antibody [2A9] - ab128117 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2A9

Anti-SPRING / TRIM9 Antibody (aa284-669, clone 2D8) - LS-C336911 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2D8

Anti-SPRING / TRIM9 Antibody (clone 2D6) - LS-C175100 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2D6

Anti-SPRING / TRIM9 Antibody (aa284-669, clone 2B5) - LS-C336905 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2B5

Anti-SPRING / TRIM9 Antibody (clone 2A9) - LS-C175098 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2A9

Anti-SPRING / TRIM9 Antibody (clone 1G10) - LS-C175101 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1G10

Anti-SPRING / TRIM9 Antibody (clone 3C9) - LS-C175114 from LifeSpan Bioscience Prices $350.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 3C9

Anti-SPRING / TRIM9 Antibody (clone 1E4) - LS-C175120 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1E4

Anti-SPRING / TRIM9 Antibody (C-Terminus) IHC-plus™ - LS-B1111 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SPRING / TRIM9 Antibody (clone 2A1) - LS-C175108 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2A1

Anti-SPRING / TRIM9 Antibody (C-Terminus) - LS-C31266 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SPRING / TRIM9 Antibody (aa540-589) - LS-C80086 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SPRING / TRIM9 Antibody (C-Terminus) - LS-C80105 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SPRING / TRIM9 Antibody (C-Terminus) - LS-C80106 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SPRING / TRIM9 Antibody (aa611-660) - LS-C109887 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SPRING / TRIM9 Antibody (aa648-676, AP) - LS-C272270 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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