TRIM9

Gene Symbol	TRIM9
Entrez Gene	114088
Alt Symbol	RNF91, SPRING
Species	Human
Gene Type	protein-coding
Description	tripartite motif containing 9
Other Description	E3 ubiquitin-protein ligase TRIM9|RING finger protein 91|homolog of rat RING finger Spring|tripartite motif-containing 9|tripartite motif-containing protein 9
Swissprots	Q9C027 D3DSB7 Q96D24 Q9C025 Q92557 Q96NI4 D3DSB8 Q9C026
Accessions	EAW65680 EAW65681 EAW65682 EAW65683 EAW65684 Q9C026 AK054781 AK055388 BAB70913 BC013414 AAH13414 BC063872 AAH63872 BF966522 D87458 BAA13398 DA101991 DA173440 T77638 XM_005267301 XP_005267358 XM_005267302 XP_005267359 XM_006720018 XP_006720081 XM_011536389 XP_011534691 XM_011536390 XP_011534692 XM_011536391 XP_011534693 XM_011536392 XP_011534694 NM_015163 NP_055978 NM_052978 NP_443210
Function	E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. {ECO:0000269|PubMed:20085810}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20085810}. Cell projection, dendrite {ECO:0000269|PubMed:20085810}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle- associated form. Associated with the cytoskeleton (By similarity). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum. {ECO:0000250}.
Tissue Specificity	Brain. Highly expressed in the cerebral cortex (at protein level). Severely decreased in the affected brain areas in Parkinson disease and dementia with Lewy bodies. {ECO:0000269|PubMed:20085810}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TRIM9 / RNF91 - H00114088-T01 from Acris Antibodies Prices $320.00 Sizes 100 µl

TRIM9 overexpression lysate - LY409342 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TRIM9 293 Cell Lysate - 404939 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TRIM9 293 Cell Lysate - 407036 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TRIM9 Overexpression Lysate (Denatured) - H00114088-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

TRIM9 Overexpression Lysate (Native) - NBL1-17316 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TRIM9 Overexpression Lysate (Native) - NBP2-07207 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TRIM9 Over-expression Lysate Product - GWB-100960 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

TRIM9 Over-expression Lysate Product - GWB-B4A904 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

TRIM9 Overexpression Lysate (Native) - NBP2-09869 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

TRIM9 Overexpression Lysate (Denatured) - H00114088-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human TRIM9 Knockdown Stable Cell Line - CSC-DC016635 from Creative biogene Category Cell Line Species Human

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