TRIM9

Gene Symbol TRIM9
Entrez Gene 114088
Alt Symbol RNF91, SPRING
Species Human
Gene Type protein-coding
Description tripartite motif containing 9
Other Description E3 ubiquitin-protein ligase TRIM9|RING finger protein 91|homolog of rat RING finger Spring|tripartite motif-containing 9|tripartite motif-containing protein 9
Swissprots Q9C027 D3DSB7 Q96D24 Q9C025 Q92557 Q96NI4 D3DSB8 Q9C026
Accessions EAW65680 EAW65681 EAW65682 EAW65683 EAW65684 Q9C026 AK054781 AK055388 BAB70913 BC013414 AAH13414 BC063872 AAH63872 BF966522 D87458 BAA13398 DA101991 DA173440 T77638 XM_005267301 XP_005267358 XM_005267302 XP_005267359 XM_006720018 XP_006720081 XM_011536389 XP_011534691 XM_011536390 XP_011534692 XM_011536391 XP_011534693 XM_011536392 XP_011534694 NM_015163 NP_055978 NM_052978 NP_443210
Function E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. {ECO:0000269|PubMed:20085810}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20085810}. Cell projection, dendrite {ECO:0000269|PubMed:20085810}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle- associated form. Associated with the cytoskeleton (By similarity). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum. {ECO:0000250}.
Tissue Specificity Brain. Highly expressed in the cerebral cortex (at protein level). Severely decreased in the affected brain areas in Parkinson disease and dementia with Lewy bodies. {ECO:0000269|PubMed:20085810}.

TRIM9 / RNF91 - H00114088-T01 from Acris Antibodies

Prices $320.00
Sizes 100 µl

TRIM9 overexpression lysate - LY409342 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

TRIM9 293 Cell Lysate - 404939 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

TRIM9 293 Cell Lysate - 407036 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

TRIM9 Overexpression Lysate (Denatured) - H00114088-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

TRIM9 Overexpression Lysate (Native) - NBL1-17316 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: TRIM9 Overexpression Lysate (Adult Normal) [NBL1-17316] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TRIM9.

TRIM9 Overexpression Lysate (Native) - NBP2-07207 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

TRIM9 Over-expression Lysate Product - GWB-100960 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

TRIM9 Over-expression Lysate Product - GWB-B4A904 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

TRIM9 Overexpression Lysate (Native) - NBP2-09869 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: TRIM9 Overexpression Lysate (Adult Normal) [NBP2-09869] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TRIM9.

TRIM9 Overexpression Lysate (Denatured) - H00114088-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human TRIM9 Knockdown Stable Cell Line - CSC-DC016635 from Creative biogene

Category Cell Line
Species Human
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