| Gene Symbol |
SLC7A3
|
| Entrez Gene |
84889
|
| Alt Symbol |
ATRC3, CAT-3, CAT3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
|
| Other Description |
cationic amino acid transporter 3
|
| Swissprots |
D3DVU7 Q5JQR2 Q8WY07 Q8N185 Q96SZ7 Q8NCA7
|
| Accessions |
CAF86874 EAX05329 EAX05330 Q8WY07 AF320612 AAL37184 AK027447 BAB55118 AK074865 BAC11253 AK075014 BAC11353 BC033816 AAH33816 DQ890885 ABM81811 DQ894039 ABM84965 NM_001048164 NP_001041629 NM_032803 NP_116192
|
| Function |
Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. {ECO:0000269|PubMed:11591158}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. {ECO:0000269|PubMed:11591158}.
|
![Western Blot: SLC7A3 Overexpression Lysate (Adult Normal) [NBP2-08343] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC7A3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14841_SLC7A3%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08343-img0001.jpg)
![Western Blot: SLC7A3 Overexpression Lysate (Adult Normal) [NBP2-05969] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC7A3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10630_SLC7A3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05969-img0001.jpg)