Gene Symbol | SLC7A3 |
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Entrez Gene | 84889 |
Alt Symbol | ATRC3, CAT-3, CAT3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 |
Other Description | cationic amino acid transporter 3 |
Swissprots | D3DVU7 Q5JQR2 Q8WY07 Q8N185 Q96SZ7 Q8NCA7 |
Accessions | CAF86874 EAX05329 EAX05330 Q8WY07 AF320612 AAL37184 AK027447 BAB55118 AK074865 BAC11253 AK075014 BAC11353 BC033816 AAH33816 DQ890885 ABM81811 DQ894039 ABM84965 NM_001048164 NP_001041629 NM_032803 NP_116192 |
Function | Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. {ECO:0000269|PubMed:11591158}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. {ECO:0000269|PubMed:11591158}. |
CAT-3 CRISPR/Cas9 KO Plasmid (h) - sc-410213 from Santa Cruz Biotechnology
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CAT-3 HDR Plasmid (h) - sc-410213-HDR from Santa Cruz Biotechnology
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CAT-3 Double Nickase Plasmid (h) - sc-410213-NIC from Santa Cruz Biotechnology
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CAT-3 Double Nickase Plasmid (h2) - sc-410213-NIC-2 from Santa Cruz Biotechnology
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CAT-3 CRISPR Activation Plasmid (h) - sc-410213-ACT from Santa Cruz Biotechnology
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CAT-3 CRISPR Activation Plasmid (h2) - sc-410213-ACT-2 from Santa Cruz Biotechnology
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CAT-3 Lentiviral Activation Particles (h) - sc-410213-LAC from Santa Cruz Biotechnology
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CAT-3 Lentiviral Activation Particles (h2) - sc-410213-LAC-2 from Santa Cruz Biotechnology
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CAT-3 siRNA (h) - sc-91259 from Santa Cruz Biotechnology
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CAT-3 shRNA Plasmid (h) - sc-91259-SH from Santa Cruz Biotechnology
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CAT-3 shRNA (h) Lentiviral Particles - sc-91259-V from Santa Cruz Biotechnology
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CAT3/SLC7A3 RNAi - H00084889-R01 from Novus Biologicals
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MISSION® esiRNA - EHU029741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2517 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2517 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11986 from Sigma-Aldrich
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SLC7A3 siRNA (Human) - CRJ3667 from Cohesion Biosciences
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SLC7A3 - MBS8200285 from MyBioSource
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shRNA set against Human SLC7A3 (NM_032803.5) - SHH412116 from Creative biogene
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Human SLC7A3 siRNA - orb274168 from Biorbyt
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SLC7A3 shRNA Plasmid (Human) - CHJ3667 from Cohesion Biosciences
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SLC7A3 miRNA 3'UTR clone - MiUTR4H-TG08134 from Creative biogene
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