| Gene Symbol |
SLC7A3
|
| Entrez Gene |
84889
|
| Alt Symbol |
ATRC3, CAT-3, CAT3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
|
| Other Description |
cationic amino acid transporter 3
|
| Swissprots |
D3DVU7 Q5JQR2 Q8WY07 Q8N185 Q96SZ7 Q8NCA7
|
| Accessions |
CAF86874 EAX05329 EAX05330 Q8WY07 AF320612 AAL37184 AK027447 BAB55118 AK074865 BAC11253 AK075014 BAC11353 BC033816 AAH33816 DQ890885 ABM81811 DQ894039 ABM84965 NM_001048164 NP_001041629 NM_032803 NP_116192
|
| Function |
Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. {ECO:0000269|PubMed:11591158}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. {ECO:0000269|PubMed:11591158}.
|