HAND1

Gene Symbol	HAND1
Entrez Gene	9421
Alt Symbol	Hxt, Thing1, bHLHa27, eHand
Species	Human
Gene Type	protein-coding
Description	heart and neural crest derivatives expressed 1
Other Description	class A basic helix-loop-helix protein 27|extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1|heart- and neural crest derivatives-expressed protein 1
Swissprots	O96004
Accessions	AAD19283 EAW61636 O96004 AF061756 AAD19280 BC021190 AAH21190 EU446688 ABZ92217 XM_005268531 XP_005268588 NM_004821 NP_004812
Function	Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'- NRTCTG-3' (non-canonical E-box) (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus, nucleoplasm {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity (By similarity). {ECO:0000250}.
Tissue Specificity	Heart.
Top Pathways	Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HAND1 full length protein - ab134618 from Abcam Category Protein Source E. coli Species Human

Human HAND1 peptide - ab47013 from Abcam Category Peptide

HAND1 Antibody Blocking Peptide - LS-E3256 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HAND1 Antibody Blocking Peptide - LS-E11937 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HAND1 Partial Recombinant Protein - H00009421-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HAND1 Protein - NBP2-23102 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

HAND1-Antibody-Center-Blocking-Peptide - BP14407c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HAND1 protein - orb168462 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

HAND1 protein (His tag) - 80R-2491 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

HAND1 / EHAND (1-215, His-tag) - AR50563PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

HAND1 / EHAND (1-215, His-tag) - AR50563PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

HAND1 / EHAND - H00009421-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HAND1 / EHAND - H00009421-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HAND1, 1-215aa, Human, His tag, E.coli - 01-P1739 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

HAND1 fusion protein - Ag1324 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HAND1 Human - PRPS-1238 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

HAND1, 1-215aa, Recombinant Protein - GWB-P0299M from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human Heart And Neural Crest Derivatives Expressed 1, His-tagged - HAND1-7171H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human HAND1, GST-tagged - HAND1-13662H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Heart And Neural Crest Derivatives Expressed Protein 1 (HAND1) - RPC519Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

HAND1 Blocking Peptide - CBP3986 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Rat, Bovine, Pig, Rabbit, Sheep

Recombinant Heart And Neural Crest Derivatives Expressed Protein 1 (HAND1) - RPC519Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Heart- and neural crest derivatives-expressed protein 1(HAND1) - CSB-YP010125HU CSB-EP010125HU CSB-BP010125HU CSB-MP010125HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HAND1, 1-215aa, Human, His tag, E.coli (Denatured) - ATGP1739 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Heart And Neural Crest Derivatives Expressed Protein 1 (HAND1) - RPC519Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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