KRT8

Gene Symbol KRT8
Entrez Gene 3856
Alt Symbol CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
Species Human
Gene Type protein-coding
Description keratin 8, type II
Other Description cytokeratin 8|cytokeratin-8|keratin, type II cytoskeletal 8|type-II keratin Kb8
Swissprots Q6P4C7 B0AZN5 Q6GMY0 A8K4H3 Q96J60 Q53GJ0 P05787 F8VXB4 Q14099 Q14716 Q6DHW5 Q14717
Accessions AAA35763 CAA52916 EAW96651 EAW96652 EAW96653 EAW96654 P05787 AI150751 AK222941 BAD96661 AK290938 BAF83627 AK310257 AK315826 BAF98717 AM392826 CAL37704 AM392892 CAL37770 BC000654 AAH00654 BC008200 AAH08200 BC011373 AAH11373 BC063513 AAH63513 BC073760 AAH73760 BC075839 AAH75839 BE300986 BM854215 BX417476 CX166336 DA051933 DA825311 DQ892637 ABM83563 DQ895875 ABM86801 M26512 AAA51542 M26513 M34225 AAA35748 M77025 U76549 AAB18966 X12882 CAA31376 X74929 CAA52882 X98614 CAA67203 Z36777 NM_001256282 NP_001243211 NM_001256293 NP_001243222 NM_002273 NP_002264 NR_045962
Function Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. {ECO:0000269|PubMed:16000376}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:19188445}. Nucleus, nucleoplasm {ECO:0000250}. Nucleus matrix {ECO:0000250}.
Tissue Specificity Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:16000376}.

Cytokeratin 8 CRISPR/Cas9 KO Plasmid (h) - sc-418254 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 HDR Plasmid (h) - sc-418254-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 Double Nickase Plasmid (h) - sc-418254-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 Double Nickase Plasmid (h2) - sc-418254-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 CRISPR Activation Plasmid (h) - sc-418254-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 CRISPR Activation Plasmid (h2) - sc-418254-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 Lentiviral Activation Particles (h) - sc-418254-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 Lentiviral Activation Particles (h2) - sc-418254-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 8 siRNA (h) - sc-35156 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytokeratin 8 shRNA Plasmid (h) - sc-35156-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytokeratin 8 shRNA (h) Lentiviral Particles - sc-35156-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytokeratin 8 RNAi - H00003856-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU112091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11405 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11405 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KRT8 siRNA (Human) - CRH2616 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KRT8 shRNA Plasmid (Human) - CHH2616 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KRT8 miRNA 3'UTR clone - MiUTR3H-01263 from Creative biogene

Species Reactivities Human
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