KRT8

Gene Symbol KRT8
Entrez Gene 3856
Alt Symbol CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
Species Human
Gene Type protein-coding
Description keratin 8, type II
Other Description cytokeratin 8|cytokeratin-8|keratin, type II cytoskeletal 8|type-II keratin Kb8
Swissprots Q6P4C7 B0AZN5 Q6GMY0 A8K4H3 Q96J60 Q53GJ0 P05787 F8VXB4 Q14099 Q14716 Q6DHW5 Q14717
Accessions AAA35763 CAA52916 EAW96651 EAW96652 EAW96653 EAW96654 P05787 AI150751 AK222941 BAD96661 AK290938 BAF83627 AK310257 AK315826 BAF98717 AM392826 CAL37704 AM392892 CAL37770 BC000654 AAH00654 BC008200 AAH08200 BC011373 AAH11373 BC063513 AAH63513 BC073760 AAH73760 BC075839 AAH75839 BE300986 BM854215 BX417476 CX166336 DA051933 DA825311 DQ892637 ABM83563 DQ895875 ABM86801 M26512 AAA51542 M26513 M34225 AAA35748 M77025 U76549 AAB18966 X12882 CAA31376 X74929 CAA52882 X98614 CAA67203 Z36777 NM_001256282 NP_001243211 NM_001256293 NP_001243222 NM_002273 NP_002264 NR_045962
Function Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. {ECO:0000269|PubMed:16000376}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:19188445}. Nucleus, nucleoplasm {ECO:0000250}. Nucleus matrix {ECO:0000250}.
Tissue Specificity Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:16000376}.

Cytokeratin 8 (E-12) - sc-374274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (E-12): sc-374274. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoskeletal localization.

Cytokeratin 8 (C51) - sc-8020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (C51): sc-8020. Western blot analysis of Cytokeratin 8 expression in MCF7 whole cell lysate.

Cytokeratin 8 (A-9) - sc-374275 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (A-9): sc-374275. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoskeletal localization.

Cytokeratin 8 (H-11) - sc-374027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (H-11): sc-374027. Western blot analysis of Cytokeratin 8 expression in A-431 whole cell lysate.

Cytokeratin 8 (T-13) - sc-241376 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cytokeratin 8 (T-13): sc-241376. Western blot analysis of Cytokeratin 8 expression in K-562 whole cell lysate.

Cytokeratin 8 (35bH11) - sc-58737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (35bH11): sc-58737. Western blot analysis of Cytokeratin 8 expression in MCF7 whole cell lysate.

Cytokeratin 8 (1E8) - sc-58736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (1E8): sc-58736. Western blot analysis of Cytokeratin 8 expression in HeLa (A,D), A-431 (B,E) and NCI-H1688 (C,F) under reducing (A,B,C) and under non-reducing (D,E,F) conditions.

Cytokeratin 8 (LP3K) - sc-53266 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (LP3K): sc-53266. Western blot analysis of Cytokeratin 8 expression in HeLa whole cell lysate.

Cytokeratin 8 (1E8-C6-B4) - sc-73480 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (1E8-C6-B4): sc-73480. Western blot analysis of Cytokeratin 8 expression in MCF7 whole cell lysate.

Cytokeratin 8 (19) - sc-130312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (19): sc-130312. Western blot analysis of human recombinant Cytokeratin 8.

Cytokeratin 8 (Ks8.7) - sc-101459 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (Ks8.7): sc-101459. Western blot analysis of Cytokeratin 8 expression in MCF7 whole cell lysate.

Cytokeratin 8 (M20) - sc-52324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 8 (M20): sc-52324. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoskeletal localization.

Cytokeratin 8/18 (NCL-5D3) - sc-52325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl ascites
Host Mouse
Clonality Monoclonal
Cytokeratin 8/18 (NCL-5D3): sc-52325. Western blot analysis of Cytokeratin 18 expression in non-transfected: sc-117752 (A) and human Cytokeratin 18 transfected: sc-112918 (B) 293T whole cell lysates.

Cytokeratin 8/18 (0.N.352) - sc-70939 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl ascites
Host Mouse
Clonality Monoclonal
Cytokeratin 8/18 (0.N.352): sc-70939. Western blot analysis of Cytokeratin 8/18 expression in Hep G2 whole cell lysate.

Cytokeratin 8/18 (SPM141) - sc-56376 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl ascites
Host Mouse
Clonality Monoclonal
Cytokeratin 8/18 (SPM141): sc-56376. Western blot analysis of Cytokeratin 8/18 expression in Hep G2 whole cell lysate.

p-Cytokeratin 8 (Ser 74) - sc-293099 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Cytokeratin 8 (Ser 74): sc-293099. Western blot analysis of Cytokeratin 8 phosphorylation expression in untreated (A) and EGF treated (B) Hep G2 whole cell lysates.

Anti-Cytokeratin 8 + 18 + 19 antibody [2A4] - ab41825 from Abcam

Prices $390.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2A4
IHC image of ab41825 staining in human kidney formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab41825, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Cytokeratin 8 (phospho S23) antibody [EP1629Y] - ab76584 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1629Y
ab76584, at a 1/100 dilution, staining Cytokeratin 8 in paraffin embedded human gastric adenocarcinoma (image 1) and human breast adenocarcinoma (image 2) tissues by Immunohistochemistry.

Anti-Cytokeratin 8 (phospho S431) antibody - ab59434 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded human colon carcinoma tissue stained with ab59434 at 1/50 dilution; in the presence or absence of the phosphopeptide.

Anti-Cytokeratin 8 (phospho S431) antibody [EP1630] - ab109452 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1630
All lanes : Anti-Cytokeratin 8 (phospho S431) antibody [EP1630] (ab109452) at 1/10000 dilutionLane 1 : HeLa lysates, untreatedLane 2 : HeLa lysates, treated with FBS and Calyculin ALysates/proteins at 10 µg per lane.

Anti-Cytokeratin 8 (phospho S432) antibody - ab192202 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytokeratin 8 (phospho S432) antibody (ab192202) at 1/500 dilutionLane 1 : EGF treated 293 whole cell lysate with antigen-specific peptideLane 2 : EGF treated 293 whole cell lysateLysates/proteins at 12.5 µg per lane.developed using the ECL technique

Anti-Cytokeratin 8 (phospho S73) antibody - ab51150 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
This image shows human breast carcinoma tissue stained with ab51150 at 1/50 dilution. The right hand image was treated with the immunising phospho-peptide, the left hand image was not.

Anti-Cytokeratin 8 (phospho S73) antibody [E431-2] - ab32579 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E431-2
Immunofluorescent staining of A431 cells using anti-Phospho-Keratin 8 (ab32579) diluted 1/250.

Anti-Cytokeratin 8 (phospho S74) antibody - ab194788 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/ Immunofluorescence of methanol fixed HeLa cells labeling Cytokeratin 8 (phospho S74) with ab194788 at a 1/100 dilution.

Anti-Cytokeratin 8+18 antibody [5D3] - ab17139 from Abcam

Prices $385.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 5D3
ab17139 staining human mammacarcinoma by IHC-P.
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