CDK16

Gene Symbol	CDK16
Entrez Gene	5127
Alt Symbol	PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase 16
Other Description	PCTAIRE-motif protein kinase 1|cell division protein kinase 16|serine/threonine-protein kinase PCTAIRE-1
Swissprots	Q00536 A8K280 B7Z7C8 J3KQP7 J3KN74
Accessions	EAW59294 EAW59295 EAW59296 EAW59297 EAW59298 Q00536 AB209465 BAD92702 AK096881 AK131486 BAD18631 AK290145 BAF82834 AK296880 BAH12447 AK301832 BAH13564 AK303849 BAH14066 BC001048 AAH01048 BC006190 AAH06190 BC009852 AAH09852 BC015607 AAH15607 BG029956 BQ187876 BT006827 AAP35473 DA816614 DA900611 X66363 CAA47006 XM_011543920 XP_011542222 XM_011543921 XP_011542223 XM_011543922 XP_011542224 XM_011543923 XP_011542225 XM_011543924 XP_011542226 XM_011543925 XP_011542227 XM_011543926 XP_011542228 XM_011543927 XP_011542229 XM_011543928 XP_011542230 XR_949017 NM_001170460 NP_001163931 NM_006201 NP_006192 NM_033018 NP_148978
Function	Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser- 336' (in vitro). {ECO:0000250, ECO:0000269|PubMed:22184064, ECO:0000269|PubMed:22796189, ECO:0000269|PubMed:22798068}.
Subcellular Location	Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
Tissue Specificity	Detected in pancreas islets (at protein level). Detected in brain and pancreas. {ECO:0000269|PubMed:22798068}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PCTAIRE1 protein fragment - ab177586 from Abcam Category Protein Prices $273.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Human PCTAIRE1 full length protein - ab132060 from Abcam Category Protein Source Wheat germ Species Human

Human PCTAIRE1 protein fragment - ab125552 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human PCTAIRE1 protein fragment - ab176035 from Abcam Category Protein Source E. coli Species Human

PCTAIRE1 Recombinant Protein - H00005127-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PCTAIRE1 Partial Recombinant Protein - H00005127-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human PCTAIRE1 Protein - H00005127-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PCTAIRE1 Protein - NBP2-22971 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

PCTAIRE1 Recombinant Protein - P4747 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

PCTAIRE1 Peptide - P2327 from Novus Biologicals Category Peptide Species Human

PCTAIRE1 Peptide - P2556 from Novus Biologicals Category Peptide Species Human

PCTAIRE1-PCTK1-Antibody-N-term-Blocking-peptide - BP7165a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PCTK1-Antibody-N-term-Blocking-peptide - BP11314a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PCTAIRE1-PCTK1-Antibody-C-term-Blocking-peptide - BP7547b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human CDK16 GST tag protein - orb84189 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Insect Species Human

PCTK1 Blocking Peptide - 33R-5866 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDK16 / PCTK1 (158-496, His-tag) - AR51243PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CDK16 / PCTK1 (158-496, His-tag) - AR51243PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CDK16 / PCTK1 - H00005127-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CDK16 / PCTK1 - H00005127-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CDK16 / PCTK1 - H00005127-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CDK16 / PCTK1 - H00005127-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CDK16 / PCTK1 - H00005127-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CDK16 / PCTK1 - H00005127-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDK16 / PCTK1 - H00005127-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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