CDK16

Gene Symbol CDK16
Entrez Gene 5127
Alt Symbol PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase 16
Other Description PCTAIRE-motif protein kinase 1|cell division protein kinase 16|serine/threonine-protein kinase PCTAIRE-1
Swissprots Q00536 A8K280 B7Z7C8 J3KQP7 J3KN74
Accessions EAW59294 EAW59295 EAW59296 EAW59297 EAW59298 Q00536 AB209465 BAD92702 AK096881 AK131486 BAD18631 AK290145 BAF82834 AK296880 BAH12447 AK301832 BAH13564 AK303849 BAH14066 BC001048 AAH01048 BC006190 AAH06190 BC009852 AAH09852 BC015607 AAH15607 BG029956 BQ187876 BT006827 AAP35473 DA816614 DA900611 X66363 CAA47006 XM_011543920 XP_011542222 XM_011543921 XP_011542223 XM_011543922 XP_011542224 XM_011543923 XP_011542225 XM_011543924 XP_011542226 XM_011543925 XP_011542227 XM_011543926 XP_011542228 XM_011543927 XP_011542229 XM_011543928 XP_011542230 XR_949017 NM_001170460 NP_001163931 NM_006201 NP_006192 NM_033018 NP_148978
Function Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser- 336' (in vitro). {ECO:0000250, ECO:0000269|PubMed:22184064, ECO:0000269|PubMed:22796189, ECO:0000269|PubMed:22798068}.
Subcellular Location Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
Tissue Specificity Detected in pancreas islets (at protein level). Detected in brain and pancreas. {ECO:0000269|PubMed:22798068}.

PCTAIRE-1 CRISPR/Cas9 KO Plasmid (h) - sc-405470 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 HDR Plasmid (h) - sc-405470-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 Double Nickase Plasmid (h) - sc-405470-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 Double Nickase Plasmid (h2) - sc-405470-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 CRISPR Activation Plasmid (h) - sc-405470-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 CRISPR Activation Plasmid (h2) - sc-405470-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 Lentiviral Activation Particles (h) - sc-405470-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 Lentiviral Activation Particles (h2) - sc-405470-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCTAIRE-1 siRNA (h) - sc-37584 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PCTAIRE-1 shRNA Plasmid (h) - sc-37584-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PCTAIRE-1 shRNA (h) Lentiviral Particles - sc-37584-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU063431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1537 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1536 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1535 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN5842 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5842 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CDK16 siRNA (Human) - CRH3409 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PCTAIRE1 RNAi - H00005127-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PCTAIRE1 RNAi - H00005127-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CDK16 - MBS8211897 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CDK16 (NM_033018.3) - SHH260529 from Creative biogene

Category siRNA
Species Reactivities Human

CDK16 shRNA Plasmid (Human) - CHH3409 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CDK16 miRNA 3'UTR clone - MiUTR3H-02998 from Creative biogene

Species Reactivities Human

CDK16 miRNA 3'UTR clone - MiUTR3H-02999 from Creative biogene

Species Reactivities Human
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