CDK16

Gene Symbol CDK16
Entrez Gene 5127
Alt Symbol PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase 16
Other Description PCTAIRE-motif protein kinase 1|cell division protein kinase 16|serine/threonine-protein kinase PCTAIRE-1
Swissprots Q00536 A8K280 B7Z7C8 J3KQP7 J3KN74
Accessions EAW59294 EAW59295 EAW59296 EAW59297 EAW59298 Q00536 AB209465 BAD92702 AK096881 AK131486 BAD18631 AK290145 BAF82834 AK296880 BAH12447 AK301832 BAH13564 AK303849 BAH14066 BC001048 AAH01048 BC006190 AAH06190 BC009852 AAH09852 BC015607 AAH15607 BG029956 BQ187876 BT006827 AAP35473 DA816614 DA900611 X66363 CAA47006 XM_011543920 XP_011542222 XM_011543921 XP_011542223 XM_011543922 XP_011542224 XM_011543923 XP_011542225 XM_011543924 XP_011542226 XM_011543925 XP_011542227 XM_011543926 XP_011542228 XM_011543927 XP_011542229 XM_011543928 XP_011542230 XR_949017 NM_001170460 NP_001163931 NM_006201 NP_006192 NM_033018 NP_148978
Function Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser- 336' (in vitro). {ECO:0000250, ECO:0000269|PubMed:22184064, ECO:0000269|PubMed:22796189, ECO:0000269|PubMed:22798068}.
Subcellular Location Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
Tissue Specificity Detected in pancreas islets (at protein level). Detected in brain and pancreas. {ECO:0000269|PubMed:22798068}.

PCTAIRE 1 Antibody - 4852 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from CAD and Neuro2A cells, using PCTAIRE 1 Antibody.

PCTAIRE-1 (C-16) - sc-174 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PCTAIRE-1 (C-16): sc-174. Western blot analysis of PCTAIRE-1 expression in U-87 MG (A), A549 (B) and MCF7 (C) whole cell lysates.

PCTAIRE-1 (G-1) - sc-166242 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCTAIRE-1 (G-1): sc-166242. Western blot analysis of PCTAIRE-1 expression in non-transfected: sc-117752 (A) and mouse PCTAIRE-1 transfected: sc-122443 (B) 293T whole cell lysates.

PCTAIRE-1 (G6.1) - sc-53410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCTAIRE-1 (G6.1): sc-53410. Western blot analysis of PCTAIRE-1 expression in mouse kidney (A) tissue extract and NIH/3T3 (B), U-87 MG (C), A549 (D) and MCF7 (E) whole cell lysates.

PCTAIRE-1 (H-70) - sc-22775 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PCTAIRE-1 (H-70): sc-22775. Western blot analysis of PCTAIRE-1 expression in non-transfected: sc-117752 (A) and mouse PCTAIRE-1 transfected: sc-122442 (B) 293T whole cell lysates.

Anti-PCTAIRE1 antibody - ab37895 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PCTAIRE1 antibody (ab37895) at 1/100 dilution + A375 cell lysate

Anti-PCTAIRE1 antibody - ab55552 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
PCTAIRE1 antibody (ab55552) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human kidney.

Anti-PCTAIRE1 antibody - ab55553 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PCTAIRE1 antibody [EPR13210] - ab181208 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13210
Flow cytometric analysis of BxPC-3 cells (2% paraformaldehyde-fixed) labeling PCTAIRE1 with ab181208 at 1/20 dilution (red) or a rabbit IgG isotype control (green). Goat anti rabbit IgG (FITC) at 1/150 dilution was used as a secondary antibody.

Anti-PCTAIRE1 antibody [EPR13210-141] - ab185542 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13210-141
All lanes : Anti-PCTAIRE1 antibody [EPR13210-141] (ab185542) at 1/5000 dilutionLane 1 : 293T cell lysateLane 2 : 293T cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-PCTAIRE1 antibody [G6.1] - ab11043 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone G6.1

Anti-CDK16 / PCTAIRE Antibody - LS-C38107 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus, AP) - LS-C280634 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus, Biotin) - LS-C280636 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus, APC) - LS-C280635 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus, Azide-free, HRP) - LS-C280638 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus, FITC) - LS-C280637 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus, PE) - LS-C280639 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (aa446-496) - LS-C291009 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (C-Terminus) - LS-C328165 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK16 / PCTAIRE Antibody (N-Terminus) - LS-C112292 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CDK16 / PCTK1 antibody LS-C112292 Western blot of Small Intestine lysate. Antibody concentration 1 ug/ml.

Anti-CDK16 / PCTAIRE Antibody (clone 4D2) - LS-C133368 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D2
Western blot of PCTK1 expression in transfected 293T cell line by PCTK1 monoclonal antibody (M01), clone 4D2.

Anti-CDK16 / PCTAIRE Antibody (aa25-75) - LS-C291008 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PCTAIRE1 by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-PCTAIRE1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-CDK16 / PCTAIRE Antibody (N-Terminus) - LS-C99041 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of PCTK1 (arrow) using rabbit polyclonal PCTK1 C-term. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PCTK1 gene (Lane 2).

PCTAIRE1 Antibody - NBP1-92248 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCTAIRE1 Antibody [NBP1-92248] - Analysis in human cell line HEK 293.
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