| Gene Symbol |
MAST2
|
| Entrez Gene |
23139
|
| Alt Symbol |
MAST205, MTSSK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
microtubule associated serine/threonine kinase 2
|
| Other Description |
microtubule associated testis specific serine/threonine protein kinase|microtubule-associated serine/threonine-protein kinase 2
|
| Swissprots |
Q8NDG1 Q5VT07 O94899 Q6P0Q8 Q9BYE8 Q96B94 Q5VT08 Q7LGC4
|
| Accessions |
EAX06948 EAX06949 Q6P0Q8 AB018350 BAA34527 AB047005 BAB40778 AK027123 AK055291 BAG51495 AK096519 BAG53313 AK309510 AL137594 CAB70833 AL540100 AL833919 CAD38775 BC006166 AAH06166 BC015816 AAH15816 BC065499 AAH65499 BM675011 CN297081 XM_005270652 XP_005270709 XM_005270654 XP_005270711 XM_005270655 XP_005270712 XM_005270656 XP_005270713 XM_006710475 XP_006710538 XM_006710477 XP_006710540 XM_011541059 XP_011539361 XM_011541060 XP_011539362 XM_011541061 XP_011539363 XM_011541062 XP_011539364 XM_011541063 XP_011539365 XM_011541064 XP_011539366 XM_011541065 XP_011539367 XM_011541066 XP_011539368 XM_011541067 XP_011539369 XM_011541068 XP_011539370 XM_011541069 XP_011539371 NM_015112 NP_055927
|
| Function |
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12117771}. Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Recruited to the sub-membranous area on interaction with CDHR2.
|
| Tissue Specificity |
Abundant in the testis. {ECO:0000269|PubMed:8902215}.
|