| Gene Symbol |
SLC5A5
|
| Entrez Gene |
6528
|
| Alt Symbol |
NIS, TDH1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 5 (sodium/iodide cotransporter), member 5
|
| Other Description |
Na(+)/I(-) cotransporter|Na(+)/I(-) symporter|sodium/iodide cotransporter|solute carrier family 5 (sodium iodide symporter), member 5
|
| Swissprots |
Q92911 O43702 Q9NYB6 Q2M335
|
| Accessions |
AAC14697 AAC62827 EAW84643 Q92911 AF260700 AAF70339 BC105047 AAI05048 BC105049 AAI05050 BX648217 D87920 BAA24835 U66088 AAB17378 XM_011528192 XP_011526494 XM_011528193 XP_011526495 XM_011528194 XP_011526496 NM_000453 NP_000444
|
| Function |
Mediates iodide uptake in the thyroid gland.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. {ECO:0000269|PubMed:8806637, ECO:0000269|PubMed:9329364}.
|
| Top Pathways |
Thyroid hormone synthesis
|