SLC5A5

Gene Symbol SLC5A5
Entrez Gene 6528
Alt Symbol NIS, TDH1
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/iodide cotransporter), member 5
Other Description Na(+)/I(-) cotransporter|Na(+)/I(-) symporter|sodium/iodide cotransporter|solute carrier family 5 (sodium iodide symporter), member 5
Swissprots Q92911 O43702 Q9NYB6 Q2M335
Accessions AAC14697 AAC62827 EAW84643 Q92911 AF260700 AAF70339 BC105047 AAI05048 BC105049 AAI05050 BX648217 D87920 BAA24835 U66088 AAB17378 XM_011528192 XP_011526494 XM_011528193 XP_011526495 XM_011528194 XP_011526496 NM_000453 NP_000444
Function Mediates iodide uptake in the thyroid gland.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. {ECO:0000269|PubMed:8806637, ECO:0000269|PubMed:9329364}.
Top Pathways Thyroid hormone synthesis

NIS (N-15) - sc-48055 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NIS (P-14) - sc-48056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NIS (P-14): sc-48056. Western blot analysis of NIS expression in TT whole cell lysate.

NIS (H-42) - sc-134515 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

NIS (D-16) - sc-48052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NIS (D-16): sc-48052. Western blot analysis of NIS expression in TT whole cell lysate.

SLC5A8 (A-15) - sc-34189 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SLC5A8 (A-15): sc-34189. Western blot analysis of SLC5A8 expression in MCF10A whole cell lysate.

Anti-Sodium Iodide Symporter antibody - ab83816 from Abcam

Prices $379.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Sodium Iodide Symporter antibody (ab83816) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysateSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Sodium Iodide Symporter antibody - ab101084 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Sodium Iodide Symporter antibody (ab101084) at 1 µg/ml + Thyroid (Human) Whole Cell Lysate - adult normal tissue (ab29636) at 20 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Sodium Iodide Symporter antibody - ab104716 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Sodium Iodide Symporter antibody (ab104716) at 1 µg/ml + COLO205 cell lysate at 10 µg

Anti-Sodium Iodide Symporter antibody [SPM186] - ab17795 from Abcam

Prices $400.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone SPM186
ab17795 staining Sodium Iodide Symporter in Rat thyrocytes (Pccl3) by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with 4% paraformaldehyde, permeabilized with 0.1% saponin and blocked with 5% BSA for 1 hour at 37°C. Samples were incubated with primary antibody (1/50 in PBS + 1% BSA + 0.1% saponin) for 16 hours at 4°C. An Alexa Fluor® 488-conjugated Goat anti-mouse IgG polyclonal (1/300) was used as the secondary antibody.See Abreview

Anti-Sodium Iodide Symporter antibody [SPM186], prediluted - ab17950 from Abcam

Host Mouse
Clonality Monoclonal
Clone SPM186
Human thyroid stained with anti-hNIS (ab17950).

Anti-Sodium Iodide Symporter antibody - N-terminal - ab199410 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Sodium Iodide Symporter antibody - N-terminal (ab199410) at 1/450 dilutionLane 1 : Human colon cancer lysateLane 2 : Human ovarian cancer lysateLysates/proteins at 40 µg per lane.

Anti-SLC5A5 / NIS Antibody (C-Terminus) - LS-C16859 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SLC5A5 / NIS Antibody (aa37-54) - LS-C16858 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SLC5A5 / NIS Antibody (C-Terminus) - LS-C16863 from LifeSpan Bioscience

Prices $845.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC5A5 / NIS Antibody (C-Terminus) - LS-C39731 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC5A5 / NIS Antibody (clone FP5A, Azide-free) - LS-C87821 from LifeSpan Bioscience

Prices $695.00, $1,055.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone FP5A

Anti-SLC5A5 / NIS Antibody (clone 14F) - LS-C152877 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 14F

Anti-SLC5A5 / NIS Antibody (clone FP5A) - LS-C87820 from LifeSpan Bioscience

Prices $280.00, $605.00, $960.00
Sizes 100 µl, 500 µl, 1 ml
Host Mouse
Clonality Monoclonal
Clone FP5A
Formalin-fixed, paraffin-embedded human thyroid gland stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of follicular epithelium.

Anti-SLC5A5 / NIS Antibody (clone FP5) - LS-C152932 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone FP5

Anti-SLC5A5 / NIS Antibody (aa468-643, clone SPM178) - LS-C189446 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone SPM178

Anti-SLC5A5 / NIS Antibody (aa625-643, clone SPM 186) - LS-C189125 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-SLC5A5 / NIS Antibody (C-Terminus) - LS-C193715 from LifeSpan Bioscience

Prices $875.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC5A5 / NIS Antibody - LS-C202771 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC5A5 / NIS Antibody (aa468-643, clone 14F, Atto 390) - LS-C228524 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 14F

Anti-SLC5A5 / NIS Antibody (aa468-643, clone 14F, Atto 488) - LS-C228525 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 14F
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