SLC5A5

Gene Symbol SLC5A5
Entrez Gene 6528
Alt Symbol NIS, TDH1
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/iodide cotransporter), member 5
Other Description Na(+)/I(-) cotransporter|Na(+)/I(-) symporter|sodium/iodide cotransporter|solute carrier family 5 (sodium iodide symporter), member 5
Swissprots Q92911 O43702 Q9NYB6 Q2M335
Accessions AAC14697 AAC62827 EAW84643 Q92911 AF260700 AAF70339 BC105047 AAI05048 BC105049 AAI05050 BX648217 D87920 BAA24835 U66088 AAB17378 XM_011528192 XP_011526494 XM_011528193 XP_011526495 XM_011528194 XP_011526496 NM_000453 NP_000444
Function Mediates iodide uptake in the thyroid gland.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. {ECO:0000269|PubMed:8806637, ECO:0000269|PubMed:9329364}.
Top Pathways Thyroid hormone synthesis

NIS CRISPR/Cas9 KO Plasmid (h) - sc-402298 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS HDR Plasmid (h) - sc-402298-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS Double Nickase Plasmid (h) - sc-402298-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS Double Nickase Plasmid (h2) - sc-402298-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS CRISPR Activation Plasmid (h) - sc-402298-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS CRISPR Activation Plasmid (h2) - sc-402298-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS Lentiviral Activation Particles (h) - sc-402298-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS Lentiviral Activation Particles (h2) - sc-402298-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIS siRNA (h) - sc-61199 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIS shRNA Plasmid (h) - sc-61199-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIS shRNA (h) Lentiviral Particles - sc-61199-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC5A5/Sodium Iodide Symporter RNAi - H00006528-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19665 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19665 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00751 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00751

SLC5A5 siRNA (Human) - CRH4422 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC5A5 - MBS8206842 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC5A5 (NM_000453.2) - SHH411740 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC5A5(NM_000453.2) - SHL010574 from Creative biogene

Category siRNA
Species Reactivities Human

SLC5A5 shRNA Plasmid (Human) - CHH4422 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC5A5 miRNA 3'UTR clone - MiUTR1H-09587 from Creative biogene

Species Reactivities Human
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