Gene Symbol | MGAT4C |
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Entrez Gene | 25834 |
Alt Symbol | GNTIVH, HGNT-IV-H |
Species | Human |
Gene Type | protein-coding |
Description | MGAT4 family, member C |
Other Description | N-acetylglucosaminyltransferase IV homolog|N-acetylglucosaminyltransferase IVc|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc|UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV|UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homolog|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C|glcNAc-T IVc|gnT-IVc|mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) |
Swissprots | B4DRH2 Q9UBM8 Q9UIU5 Q4G199 |
Accessions | BAA83087 EAW97402 Q9UBM8 AK127727 BAG54560 AK299253 BAG61284 BC026068 AAH26068 BC035851 BC064141 AAH64141 BI667691 DA795621 HG505047 XM_005268776 XP_005268833 XM_005268779 XP_005268836 XM_011538149 XP_011536451 XM_011538150 XP_011536452 XM_011538151 XP_011536453 XM_011538152 XP_011536454 XM_011538153 XP_011536455 XM_011538154 XP_011536456 XM_011538155 XP_011536457 XM_011538156 XP_011536458 XM_011538157 XP_011536459 XM_011538158 XP_011536460 XM_011538159 XP_011536461 XM_011538160 XP_011536462 NM_013244 NP_037376 |
Function | Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). {ECO:0000250, ECO:0000269|PubMed:10962001}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas. {ECO:0000269|PubMed:10570912}. |
Top Pathways | N-Glycan biosynthesis |
Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), Human, ELISA Kit - CSB-EL013778HU from ARP American Research Products
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), Human, ELISA Kit - E01A1915 from ARP American Research Products
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Alpha 1, 3 mannosyl glycoprotein 4 beta N acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7210491 from MyBioSource
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Alpha 1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7228306 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7246379 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7213620 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7241313 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7204738 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7212718 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7213239 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7216824 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7231940 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7214030 from MyBioSource
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Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C), ELISA Kit - MBS7200997 from MyBioSource
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mannosyl (alpha-1, 3-) -glycoprotein beta-1, 4-N-acetylglucosaminyltransferase, isozyme C (putative) , ELISA Kit - MBS901284 from MyBioSource
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Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C(MGAT4C) ELISA kit - CSB-EL013778HU from Cusabio
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Human MGAT4C ELISA Kit - E001448 from Biobool
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Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C) ELISA Kit - AE33589HU from ARP American Research Products
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