Gene Symbol | BTG2 |
---|---|
Entrez Gene | 7832 |
Alt Symbol | PC3, TIS21 |
Species | Human |
Gene Type | protein-coding |
Description | BTG family, member 2 |
Other Description | B-cell translocation gene 2|NGF-inducible anti-proliferative protein PC3|nerve growth factor-inducible anti-proliferative|pheochromacytoma cell-3|protein BTG2 |
Swissprots | P78543 Q5VUT0 Q3KR25 A0A024R986 |
Accessions | AAL05626 EAW91475 EAW91476 P78543 BC105948 AAI05949 BC105949 AAI05950 EU446924 ABZ92453 U72649 AAB37580 Y09943 CAA71074 NM_006763 NP_006754 |
Function | Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. {ECO:0000250, ECO:0000269|PubMed:12771185, ECO:0000269|PubMed:15788397, ECO:0000269|PubMed:18337750, ECO:0000269|PubMed:18773938, ECO:0000269|PubMed:23236473}. |
Top Pathways | RNA degradation |
BTG2 (C-12) - sc-30342 from Santa Cruz Biotechnology
|
||||||||||
BTG2 (H-50) - sc-33775 from Santa Cruz Biotechnology
|
||||||||||
BTG2 (S-20) - sc-18543 from Santa Cruz Biotechnology
|
||||||||||
BTG2 (Q-22) - sc-130985 from Santa Cruz Biotechnology
|
||||||||||
Anti-BTG2 antibody - ab197362 from Abcam
|
||||||||||
Anti-BTG2 antibody - ab58219 from Abcam
|
||||||||||
Anti-BTG2 antibody - ab85051 from Abcam
|
||||||||||
Anti-BTG2 antibody - ab195598 from Abcam
|
||||||||||
Anti-BTG2 Antibody - LS-C155108 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69, AP) - LS-C252757 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69, APC) - LS-C252758 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69, Biotin) - LS-C252759 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa72-121) - LS-C29836 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69, FITC) - LS-C252760 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69, Azide-free, HRP) - LS-C252761 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69, PE) - LS-C252762 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody - LS-C136897 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa40-69) - LS-C319901 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (N-Terminus) - LS-C109811 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (clone 1A5) - LS-C198499 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (clone 1G3) - LS-C340446 from LifeSpan Bioscience
|
||||||||||
Anti-BTG2 Antibody (aa33-61) - LS-C156884 from LifeSpan Bioscience
|
||||||||||
BTG2 Antibody - NBP1-81215 from Novus Biologicals
|
||||||||||
BTG2 Antibody (1B8) - H00007832-M02 from Novus Biologicals
|
||||||||||
BTG2 Antibody (1A5) - H00007832-M01 from Novus Biologicals
|