| Gene Symbol | BTG2 |
|---|---|
| Entrez Gene | 7832 |
| Alt Symbol | PC3, TIS21 |
| Species | Human |
| Gene Type | protein-coding |
| Description | BTG family, member 2 |
| Other Description | B-cell translocation gene 2|NGF-inducible anti-proliferative protein PC3|nerve growth factor-inducible anti-proliferative|pheochromacytoma cell-3|protein BTG2 |
| Swissprots | P78543 Q5VUT0 Q3KR25 A0A024R986 |
| Accessions | AAL05626 EAW91475 EAW91476 P78543 BC105948 AAI05949 BC105949 AAI05950 EU446924 ABZ92453 U72649 AAB37580 Y09943 CAA71074 NM_006763 NP_006754 |
| Function | Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. {ECO:0000250, ECO:0000269|PubMed:12771185, ECO:0000269|PubMed:15788397, ECO:0000269|PubMed:18337750, ECO:0000269|PubMed:18773938, ECO:0000269|PubMed:23236473}. |
| Top Pathways | RNA degradation |
BTG family, member 2, ELISA Kit - MBS9317342 from MyBioSource
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Human BTG2 ELISA Kit - E005404 from Biobool
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