Gene Symbol | PODXL2 |
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Entrez Gene | 50512 |
Alt Symbol | EG, PODLX2 |
Species | Human |
Gene Type | protein-coding |
Description | podocalyxin-like 2 |
Other Description | endoglycan|podocalyxin-like protein 2 |
Swissprots | Q8WUV6 Q6UVY4 Q9NZ53 |
Accessions | EAW79337 EAW79338 Q9NZ53 AF219137 AAF44629 AL524055 AY359096 AAQ89454 BC019330 AAH19330 BC052585 AAH52585 DB543702 NM_015720 NP_056535 |
Function | Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L- selectins. {ECO:0000269|PubMed:18606703}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells. {ECO:0000269|PubMed:10722749, ECO:0000269|PubMed:18606703}. |
Podocalyxin-like protein 2, ELISA Kit - MBS281223 from MyBioSource
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Custom Human Endoglycan ELISA - ELH-ENGLN from RayBiotech
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Custom Human Endoglycan Elisa kit - orb305257 from Biorbyt
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Human Endoglycan ELISA - RAB1432 from Sigma-Aldrich
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Custom Human Endoglycan ELISA - ELH-ENGLN-1 from RayBiotech
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Human PODXL2 ELISA Kit - E029935 from Biobool
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Human Podocalyxin-like protein 2 (PODXL2) ELISA Kit - AE26754HU from ARP American Research Products
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