ATG13

Gene Symbol ATG13
Entrez Gene 9776
Alt Symbol KIAA0652, PARATARG8
Species Human
Gene Type protein-coding
Description autophagy related 13
Other Description ATG13 autophagy related 13 homolog|autophagy-related protein 13
Swissprots Q9BRL3 B4DFI4 Q9H8B0 D3DQQ2 D3DQQ1 E9PQZ8 Q53EN6 O75143
Accessions EAW67985 EAW67986 EAW67987 EAW67988 EAW67989 EAW67990 EAW67991 O75143 AB014552 BAA31627 AF052175 AK000705 AK023867 BAB14707 AK223603 BAD97323 AK289641 BAF82330 AK293109 BAF85798 AK294110 BAG57445 AK296526 BAG59157 AK315925 BAH14296 BC001331 AAH01331 BC002378 AAH02378 BC006191 AAH06191 CD675643 DA195671 GQ129361 ACT64495 GQ129362 ACT64496 HQ448260 ADQ32740 XM_005253262 XP_005253319 XM_005253263 XP_005253320 XM_005253265 XP_005253322 XM_005253266 XP_005253323 XM_005253268 XP_005253325 XM_006718394 XP_006718457 XM_006718395 XP_006718458 XM_006718396 XP_006718459 XM_011520493 XP_011518795 XM_011520494 XP_011518796 XM_011520495 XP_011518797 XM_011520496 XP_011518798 XM_011520497 XP_011518799 XM_011520498 XP_011518800 XM_011520499 XP_011518801 XM_011520500 XP_011518802 XM_011520501 XP_011518803 XM_011520502 XP_011518804 XM_011520503 XP_011518805 NM_001142673 NP_001136145 NM_001205119 NP_001192048 NM_001205120 NP_001192049 NM_001205121 NP_001192050 NM_001205122 NP_001192051 NM_014741 NP_055556
Function Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. {ECO:0000269|PubMed:18936157, ECO:0000269|PubMed:19211835, ECO:0000269|PubMed:19225151, ECO:0000269|PubMed:19287211, ECO:0000269|PubMed:21795849, ECO:0000269|PubMed:21855797}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Preautophagosomal structure {ECO:0000250}. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. {ECO:0000250}.
Top Pathways Regulation of autophagy

Atg13 (D4P1K) Rabbit mAb - 13273 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4P1K
Western blot analysis of extracts from RD, PANC-1, and A20 cells using Atg13 (D4P1K) Rabbit mAb.

Atg13 (E1Y9V) Rabbit mAb - 13468 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1Y9V
Western blot analysis of extracts from various cell lines using Atg13 (E1Y9V) Rabbit mAb.

Atg13 Antibody - 6940 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Atg13 (E-15) - sc-240548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Atg13 (N-14) - sc-240546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KIAA0652 antibody - ab105392 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KIAA0652 antibody (ab105392) at 1 µg/mlLane 1 : Rat heart tissue lysate without blocking peptideLane 2 : Rat heart tissue lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-KIAA0652 antibody - ab103201 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KIAA0652 antibody (ab103201) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-KIAA0652 antibody - ab156079 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-KIAA0652 antibody (ab156079) at 1/100 dilution + MCF-7 cell line lysate at 35 µg

Anti-KIAA0652 / ATG13 Antibody (C-Terminus) IHC-plus™ - LS-B10936 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KIAA0652 / ATG13 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10936 concentration 5 ug/ml.

Anti-KIAA0652 / ATG13 Antibody - LS-C331070 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded mouse lung using ATG13 antibody at dilution of 1:200 (200x lens).

Anti-KIAA0652 / ATG13 Antibody (aa1-30) IHC-plus™ - LS-B11831 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-KIAA0652 / ATG13 Antibody - LS-C153227 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa333-362, APC) - LS-C232943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa333-362, AP) - LS-C232941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa80-129) - LS-C151704 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIAA0652 / ATG13 antibody Western Blot of 293T.

Anti-KIAA0652 / ATG13 Antibody (phospho-Ser355) - LS-C157560 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot of ATG13 Antibody (Phospho S355) Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Anti-KIAA0652 / ATG13 Antibody (N-Terminus) - LS-C151705 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIAA0652 / ATG13 antibody Western Blot of PANC1.

Anti-KIAA0652 / ATG13 Antibody (aa333-362, Biotin) - LS-C232944 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa333-362, FITC) - LS-C232945 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (phospho-Ser318) - LS-C153855 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of affinity purified anti-ATG13 pS318 antibody shows detection of phosphorylated ATG13 in 293T cells engineered to coexpress Ulk1 and Atg13 (Ulk1 + Atg13). In the left lane was loaded kinase-dead hypophosphorylated Ulk1-K46A mutant + ATG13. The right lane contains the 293T Ulk1 + ATG13 lysate and shows detection at approximately 57 kDa. The antibody was purified and resolved by SDS-PAGE, then transferred to nitrocellulose membrane. The membrane was blocked with 5% Blotto (p/n B501-0500) and probed with the primary antibody at 1g/mL overnight at 4C. After washing, the membrane was probed with Goat Anti-Rabbit HRP secondary 1:5000 in detection buffer (p/n MB-070) for 45 minutes at room temperature. In collaboration with Charles Dorsey at Eli Lilly, Indianapolis, IN and John Cleveland at Scripps, Jupiter, FL.

Anti-KIAA0652 / ATG13 Antibody - LS-C153856 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of affinity purified anti-ATG13 antibody shows detection of ATG13 in 293T cells engineered to coexpress Ulk1 and Atg13 (Ulk1 + Atg13), right lane, but not in the left lane in which was loaded kinase-dead hypophosphorylated Ulk1-K46A mutant + ATG13. Detection is demonstrated at approximately 57 kDa. The antibody was purified and resolved by SDS-PAGE, then transferred to nitrocellulose membrane. The membrane was blocked with 5% Blotto (p/n B501-0500) and probed with the primary antibody at 1g/mL overnight at 4C. After washing, the membrane was probed with Goat Anti-Rabbit HRP secondary 1:5000 in detection buffer (p/n MB-070) for 45 minutes at room temperature. In collaboration with Charles Dorsey at Eli Lilly, Indianapolis, IN and John Cleveland at Scripps, Jupiter, FL.

Anti-KIAA0652 / ATG13 Antibody (aa333-362, PE) - LS-C232946 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa1-30, AP) - LS-C232947 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa1-30, Biotin) - LS-C232949 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0652 / ATG13 Antibody (aa1-30, APC) - LS-C232948 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more