ATG13

Gene Symbol	ATG13
Entrez Gene	9776
Alt Symbol	KIAA0652, PARATARG8
Species	Human
Gene Type	protein-coding
Description	autophagy related 13
Other Description	ATG13 autophagy related 13 homolog|autophagy-related protein 13
Swissprots	Q9BRL3 B4DFI4 Q9H8B0 D3DQQ2 D3DQQ1 E9PQZ8 Q53EN6 O75143
Accessions	EAW67985 EAW67986 EAW67987 EAW67988 EAW67989 EAW67990 EAW67991 O75143 AB014552 BAA31627 AF052175 AK000705 AK023867 BAB14707 AK223603 BAD97323 AK289641 BAF82330 AK293109 BAF85798 AK294110 BAG57445 AK296526 BAG59157 AK315925 BAH14296 BC001331 AAH01331 BC002378 AAH02378 BC006191 AAH06191 CD675643 DA195671 GQ129361 ACT64495 GQ129362 ACT64496 HQ448260 ADQ32740 XM_005253262 XP_005253319 XM_005253263 XP_005253320 XM_005253265 XP_005253322 XM_005253266 XP_005253323 XM_005253268 XP_005253325 XM_006718394 XP_006718457 XM_006718395 XP_006718458 XM_006718396 XP_006718459 XM_011520493 XP_011518795 XM_011520494 XP_011518796 XM_011520495 XP_011518797 XM_011520496 XP_011518798 XM_011520497 XP_011518799 XM_011520498 XP_011518800 XM_011520499 XP_011518801 XM_011520500 XP_011518802 XM_011520501 XP_011518803 XM_011520502 XP_011518804 XM_011520503 XP_011518805 NM_001142673 NP_001136145 NM_001205119 NP_001192048 NM_001205120 NP_001192049 NM_001205121 NP_001192050 NM_001205122 NP_001192051 NM_014741 NP_055556
Function	Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. {ECO:0000269|PubMed:18936157, ECO:0000269|PubMed:19211835, ECO:0000269|PubMed:19225151, ECO:0000269|PubMed:19287211, ECO:0000269|PubMed:21795849, ECO:0000269|PubMed:21855797}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Preautophagosomal structure {ECO:0000250}. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. {ECO:0000250}.
Top Pathways	Regulation of autophagy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KIAA0652 protein (Tagged) - ab127606 from Abcam Category Protein Source E. coli Species Human

KIAA0652 / ATG13 Antibody Blocking Peptide - LS-E23475 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KIAA0652 / ATG13 Antibody Blocking Peptide - LS-E23476 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KIAA0652 / ATG13 Antibody Blocking Peptide - LS-E30942 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KIAA0652 / ATG13 Antibody Blocking Peptide - LS-E10394 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ATG13 Protein - H00009776-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATG13-Antibody-N-term-Blocking-Peptide - BP9928a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ATG13 Peptide - GTX85183-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

ATG13 - H00009776-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ATG13 - H00009776-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ATG13 control peptide - AP26240CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ATG13 Peptide - 5799P from ProSci Category Peptide Species Human

KIAA0652 fusion protein - ag13090 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

KIAA0652 fusion protein - Ag12968 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human ATG13, GST-tagged - ATG13-6972H from Creative Biomart Category Protein Source E. coli Species Human

ATG13 protein-GST fusion - 009-001-R44 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

ATG13 protein-GST fusion - 009-001-R44S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

Recombinant Human Autophagy-related protein 13(ATG13) - CSB-YP012203HU CSB-EP012203HU CSB-BP012203HU CSB-MP012203HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ATG13, Recombinant Protein - MBS515082 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source E.coli Species Human

Autophagy-related protein 13 (ATG13) , Recombinant Protein - MBS1170705 from MyBioSource Category Protein Prices $2,150.00, $2,150.00, $2,615.00, $2,615.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ATG13 Protein - NBP1-87858PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ATG13-Blocking-Peptide-Center-S355 - BP19789c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-ATG13S355-Blocking-Peptide - BP3834a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

ATG13 Peptide, Human - M34GP01094H from Creative Peptides Category Peptide Source Synthetic. Species Human

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