Gene Symbol | RNASET2 |
---|---|
Entrez Gene | 8635 |
Alt Symbol | RNASE6PL, bA514O12.3 |
Species | Human |
Gene Type | protein-coding |
Description | ribonuclease T2 |
Other Description | ribonuclease 6 |
Swissprots | Q9BZ46 Q8TCU2 E1P5C3 O00584 Q5T8Q0 B2RDA7 Q9BZ47 |
Accessions | EAW47511 EAW47512 EAW47513 EAW47514 EAW47515 EAW47516 EAW47517 EAW47518 EAW47519 O00584 AJ419865 CAD12030 AJ419866 CAD12031 AJ419867 CAD12032 AK001769 AK124363 AK315467 BAG37854 BC001660 AAH01660 BC001819 AAH01819 BC019871 BC036282 BC039713 AAH39713 BC041056 BC051912 AAH51912 CB130245 U85625 AAC51363 NM_003730 NP_003721 |
Function | Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism. {ECO:0000250, ECO:0000269|PubMed:16620762, ECO:0000269|PubMed:19525954, ECO:0000269|PubMed:22735700}. |
Subcellular Location | Secreted. Lysosome lumen. Endoplasmic reticulum lumen. Note=Subcellular fractionation of transfected ovarian cancer cells reveals full-length RNASET2 in the endoplasmic reticulum fraction and the 2 smaller RNASET2 proteolytic products in the lysosome fraction. |
Tissue Specificity | Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain. {ECO:0000269|PubMed:19525954}. |
Human Ribonuclease T2 full length protein - ab152900 from Abcam
|
||||||||||
RNASET2 Antibody Blocking Peptide - LS-E476 from LifeSpan Bioscience
|
||||||||||
RNASET2 Antibody Blocking Peptide - LS-E11676 from LifeSpan Bioscience
|
||||||||||
RNASET2 Antibody Blocking Peptide - LS-E31245 from LifeSpan Bioscience
|
||||||||||
Recombinant Human RNASET2 Protein - H00008635-P01 from Novus Biologicals
|
||||||||||
RNT2-Antibody-N-term-Blocking-peptide - BP10764a from Abgent, a WuXi AppTec company
|
||||||||||
RNASET2 Protein Lysate (APL10276) - APL10276 from Aviva Systems Biology
|
||||||||||
Human RNASET2 protein (His Tag) - orb139594 from Biorbyt
|
||||||||||
RNASET2 Blocking Peptide - 33R-8208 from Fitzgerald
|
||||||||||
Human Ribonuclease T2 Protein - abx068929 from Abbexa
|
||||||||||
RNASET2 - H00008635-P01-10 from Acris Antibodies
|
||||||||||
RNASET2 - H00008635-P01-25 from Acris Antibodies
|
||||||||||
RNASET2 (C-term) Control Peptide - AP55670CP-N from Acris Antibodies
|
||||||||||
Ribonuclease T2 (RNASET2), Human - 20-6271 from ARP American Research Products
|
||||||||||
RNASET2 Peptide - 6763P from ProSci
|
||||||||||
RNASET2 fusion protein - ag4695 from Proteintech Group
|
||||||||||
Recombinant Ribonuclease T2 (RNASET2) - RPA113Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Ribonuclease T2 (RNASET2) - RPA113Mu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Ribonuclease T2 (RNASET2) - RPA113Mu02 from Uscn Life Science Inc.
|
||||||||||
Recombinant Ribonuclease T2 (RNASET2) - RPA113Ra01 from Uscn Life Science Inc.
|
||||||||||
Human RNASET2 Protein (His Tag) - 13509-H08B-10 from Sino Biological
|
||||||||||
Recombinant Ribonuclease T2 (RNASET2) - RPA113Hu01 from Cloud-clone
|
||||||||||
Recombinant Human Ribonuclease T2(RNASET2) - CSB-YP019810HU CSB-EP019810HU CSB-BP019810HU CSB-MP019810HU from Cusabio
|
||||||||||
Ribonuclease T2 (RNASET2) - RPU143656 from Biomatik
|
||||||||||
RNASET2 - TP308746 from Acris Antibodies
|