RNASET2

Gene Symbol RNASET2
Entrez Gene 8635
Alt Symbol RNASE6PL, bA514O12.3
Species Human
Gene Type protein-coding
Description ribonuclease T2
Other Description ribonuclease 6
Swissprots Q9BZ46 Q8TCU2 E1P5C3 O00584 Q5T8Q0 B2RDA7 Q9BZ47
Accessions EAW47511 EAW47512 EAW47513 EAW47514 EAW47515 EAW47516 EAW47517 EAW47518 EAW47519 O00584 AJ419865 CAD12030 AJ419866 CAD12031 AJ419867 CAD12032 AK001769 AK124363 AK315467 BAG37854 BC001660 AAH01660 BC001819 AAH01819 BC019871 BC036282 BC039713 AAH39713 BC041056 BC051912 AAH51912 CB130245 U85625 AAC51363 NM_003730 NP_003721
Function Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism. {ECO:0000250, ECO:0000269|PubMed:16620762, ECO:0000269|PubMed:19525954, ECO:0000269|PubMed:22735700}.
Subcellular Location Secreted. Lysosome lumen. Endoplasmic reticulum lumen. Note=Subcellular fractionation of transfected ovarian cancer cells reveals full-length RNASET2 in the endoplasmic reticulum fraction and the 2 smaller RNASET2 proteolytic products in the lysosome fraction.
Tissue Specificity Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain. {ECO:0000269|PubMed:19525954}.

RNase T2 (E-5) - sc-393729 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RNase T2 (E-5): sc-393729. Western blot analysis of RNase T2 expression in SP2/0 (A), I-11.15 (B) and NCI-H460 (C) whole cell lysates.

RNase T2 (D-13) - sc-109016 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RNase T2 (S-14) - sc-109020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Ribonuclease T2 antibody - ab107313 from Abcam

Prices $385.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab107313 stained LoVo cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab107313 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Ribonuclease T2 antibody - ab140191 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ribonuclease T2 antibody (ab140191) at 1 µg/mlLane 1 : SW480 cell lysateLane 2 : SW480 cell lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-Ribonuclease T2 antibody - ab86165 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling Ribonuclease T2 with ab86165 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining seen in the cytoplasm of alveolar cells. type I and II. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - Ribonuclease T2. Right - Merge.

Anti-Ribonuclease T2 antibody - ab169655 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Ribonuclease T2 antibody (ab169655) at 1 µg/mlLane 1 : Ribonuclease T2-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-Ribonuclease T2 antibody - C-terminal - ab174738 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed,  paraffin embedded Human kidney tissue labeling Ribonuclease T2 with ab174738 at 5 µg/ml.

Anti-RNASET2 Antibody (aa10-36, FITC) - LS-C268434 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa10-36, PE) - LS-C268438 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa10-36, Azide-free, HRP) - LS-C268435 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa10-36, AP) - LS-C285097 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa10-36, APC) - LS-C285098 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa10-36, Biotin) - LS-C285099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa25-256, FITC) - LS-C301512 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa25-256, Biotin) - LS-C298294 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa13-40) - LS-C324759 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASET2 Antibody (aa107-156) - LS-C101428 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RNASET2 antibody LS-C101428 Western blot of 293T cell lysate.

Anti-RNASET2 Antibody (aa25-256) - LS-C296280 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant RNASET2.

Anti-RNASET2 Antibody (aa32-259) - LS-C314395 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant RNASET2.

Anti-RNASET2 Antibody - LS-C346367 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal
Western blot blot of extracts of NCI-H460 cell line, using RNASET2 antibody.

Anti-RNASET2 Antibody (aa10-36) - LS-C162673 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RNT2 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human spleen carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RNASET2 Antibody (C-Terminus) IHC-plus™ - LS-B8807 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RNASET2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

RNASET2 Antibody - NBP1-88753 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RNASET2 Antibody - NBP1-80017 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RNASET2 Antibody [NBP1-80017] - 293T cells lysate, concentration 0.2-1 ug/ml.
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