| Gene Symbol |
SCAI
|
| Entrez Gene |
286205
|
| Alt Symbol |
C9orf126, NET40
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
suppressor of cancer cell invasion
|
| Other Description |
protein SCAI|suppressor of cancer cell invasion protein
|
| Swissprots |
Q8N1I4 Q5T163 Q3SXZ1 Q8N9R8 Q3SXZ2
|
| Accessions |
EAW87608 EAW87609 Q8N9R8 AF086497 AK021820 AK093983 AK098024 BAC05217 BC029431 BC037940 BC104030 AAI04031 BC104031 AAI04032 BC104032 AAI04033 BM873972 DB048788 XR_929767 XR_929768 NM_001144877 NP_001138349 NM_173690 NP_775961
|
| Function |
Tumor suppressor which functions to suppress MKL1- induced SRF transcriptional activity. May function in the RHOA- DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1. {ECO:0000269|PubMed:19350017}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:19350017}. Cytoplasm {ECO:0000269|PubMed:19350017}. Note=Nuclear localization is required for inhibition of MKL1. {ECO:0000250}.
|