Gene Symbol | SCAI |
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Entrez Gene | 286205 |
Alt Symbol | C9orf126, NET40 |
Species | Human |
Gene Type | protein-coding |
Description | suppressor of cancer cell invasion |
Other Description | protein SCAI|suppressor of cancer cell invasion protein |
Swissprots | Q8N1I4 Q5T163 Q3SXZ1 Q8N9R8 Q3SXZ2 |
Accessions | EAW87608 EAW87609 Q8N9R8 AF086497 AK021820 AK093983 AK098024 BAC05217 BC029431 BC037940 BC104030 AAI04031 BC104031 AAI04032 BC104032 AAI04033 BM873972 DB048788 XR_929767 XR_929768 NM_001144877 NP_001138349 NM_173690 NP_775961 |
Function | Tumor suppressor which functions to suppress MKL1- induced SRF transcriptional activity. May function in the RHOA- DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1. {ECO:0000269|PubMed:19350017}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:19350017}. Cytoplasm {ECO:0000269|PubMed:19350017}. Note=Nuclear localization is required for inhibition of MKL1. {ECO:0000250}. |
SCAI Antibody Blocking Peptide - LS-E23097 from LifeSpan Bioscience
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C9orf126-Antibody-C-term-Blocking-Peptide - BP10595b from Abgent, a WuXi AppTec company
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SCAI (N-terminal region) - SX3845 from ECM Biosciences
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Chromosome 9 open reading frame 126 (C9orf126), transcript variant 1 (transcript variant 1) - TP312280 from Acris Antibodies
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SCAI Recombinant Protein Antigen - NBP1-86711PEP from Novus Biologicals
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SCAI Peptide, Human - M34GP13817H from Creative Peptides
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Protein SCAI (SCAI), Recombinant Protein - MBS7029270 from MyBioSource
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