PLXND1

Gene Symbol PLXND1
Entrez Gene 23129
Alt Symbol PLEXD1
Species Human
Gene Type protein-coding
Description plexin D1
Other Description plexin-D1
Swissprots Q6PJS9 C9JPZ6 Q9BTQ2 Q9Y4D7 Q8IZJ2 A7E2C6
Accessions EAW79238 EAW79239 EAW79240 Q9Y4D7 AB014520 BAA31595 AK026388 AK299425 BAG61405 AY116661 AAM49063 BC003526 AAH03526 BC011848 AAH11848 BC030110 BC044228 AAH44228 BC062465 AAH62465 BC150280 AAI50281 BU527983 CX761094 XM_011512588 XP_011510890 XM_011512589 XP_011510891 XM_011512590 XP_011510892 XM_011512591 XP_011510893 XM_011512592 XP_011510894 XR_924116 NM_015103 NP_055918
Function Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E. {ECO:0000250, ECO:0000269|PubMed:20385769}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes. {ECO:0000269|PubMed:12412018}.

Plexin D1 peptide - ab106212 from Abcam

Category Peptide

Plexin D1 peptide (1683-1694) - ab45701 from Abcam

Category Peptide
Species Human

PLXND1 / Plexin D1 Antibody Blocking Peptide - LS-E25835 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PLXND1 / Plexin D1 Antibody Blocking Peptide - LS-E7428 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Phospho-PLXND1Y1642-Antibody-Blocking-peptide - BP3584a from Abgent, a WuXi AppTec company

Category Peptide
Prices $120.00
Sizes 100 µg

Plexin D1 blocking peptide - GTX89601-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Dog, Pig, Bovine

Recombinant Human Plexin D1, CF - 4160-PD-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Leu47-Ala1271 with a C-terminal 6-His tag

Plexin D1 Peptide - AC21-0667-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

Plexin D1 Peptide - 46-202P from ProSci

Category Peptide
Species Human, Mouse

Recombinant Human Plexin D1 Protein, CF - 4160-PD from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Mouse myeloma cell line, NS0-derived Leu47-Ala1271 with a C-terminal 6-His tag
Species Human

Plexin D1 (Cytoplasmic domain) - PX4405 from ECM Biosciences

Category Peptide
Prices $55.00
Sizes 50 μg
Western blot analysis of Plexin D1 expression in human endothelial cells (HUVEC) (lanes 1-6). The blots were probed with rabbit polyclonals anti-Plexin D1 (Sema domain) (lanes 1 & 2), anti-Plexin D1 (Cytoplasmic domain) (lanes 3 & 4), and anti-Plexin D1 (a.a. 1635-1647) (lanes 5 & 6). Each antibody was used in the presence of their respective blocking peptide (lanes 2, 4 & 6).

Plexin D1 (Sema Domain) - PX4425 from ECM Biosciences

Category Peptide
Prices $55.00
Sizes 50 μg
Western blot analysis of Plexin D1 expression in human endothelial cells (HUVEC) (lanes 1-6). The blots were probed with rabbit polyclonals anti-Plexin D1 (Sema domain) (lanes 1 & 2), anti-Plexin D1 (Cytoplasmic domain) (lanes 3 & 4), and anti-Plexin D1 (a.a. 1635-1647) (lanes 5 & 6). Each antibody was used in the presence of their respective blocking peptide (lanes 2, 4 & 6).

Plexin D1 (a.a. 1635-1647) - PX3075 from ECM Biosciences

Category Peptide
Prices $55.00
Sizes 50 μg
Western blot analysis of Plexin D1 expression in human endothelial cells (HUVEC) (lanes 1-6). The blots were probed with rabbit polyclonals anti-Plexin D1 (Sema domain) (lanes 1 & 2), anti-Plexin D1 (Cytoplasmic domain) (lanes 3 & 4), and anti-Plexin D1 (a.a. 1635-1647) (lanes 5 & 6). Each antibody was used in the presence of their respective blocking peptide (lanes 2, 4 & 6).

Plexin D1, Peptide - MBS425962 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Dog, Pig, Bovine

Phospho-PLXND1Y1367-Antibody-Blocking-peptide - BP3686a from Abgent, a WuXi AppTec company

Category Peptide
Prices $120.00
Sizes 100 µg

PLXND1 Peptide, Human - M34GP11994H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PLXND1 Immunizing peptide - orb17214 from Biorbyt

Category Peptide
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