PLXND1

Gene Symbol PLXND1
Entrez Gene 23129
Alt Symbol PLEXD1
Species Human
Gene Type protein-coding
Description plexin D1
Other Description plexin-D1
Swissprots Q6PJS9 C9JPZ6 Q9BTQ2 Q9Y4D7 Q8IZJ2 A7E2C6
Accessions EAW79238 EAW79239 EAW79240 Q9Y4D7 AB014520 BAA31595 AK026388 AK299425 BAG61405 AY116661 AAM49063 BC003526 AAH03526 BC011848 AAH11848 BC030110 BC044228 AAH44228 BC062465 AAH62465 BC150280 AAI50281 BU527983 CX761094 XM_011512588 XP_011510890 XM_011512589 XP_011510891 XM_011512590 XP_011510892 XM_011512591 XP_011510893 XM_011512592 XP_011510894 XR_924116 NM_015103 NP_055918
Function Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E. {ECO:0000250, ECO:0000269|PubMed:20385769}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes. {ECO:0000269|PubMed:12412018}.

plexin-D1 (C-18) - sc-46244 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

plexin-D1 (E-13) - sc-46245 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

plexin-D1 (H-70) - sc-67145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
plexin-D1 (H-70): sc-67145. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic staining of glandular cells.

plexin-D1 (P-15) - sc-46246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

plexin-D1 (S-20) - sc-46247 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Plexin D1 antibody - ab28762 from Abcam

Prices $388.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab28762 at 1/300 dilution, staining Plexin D1 in mouse brain tissue sections by IHC-P (Formalin / PFA fixed prafaffin embedded sections). Tissue underwent formaldehyde fixation, heat mediated antigen retrieval in Citrate buffer pH 6.0 and blocked in 5% serum for 1 hour. The primary antibody was used at 1/300 dillution for 1 hour. A Biotin-conjugated rabbit polyclonal to goat IgG was used as secondary at 1/250 dillution.

Anti-Plexin D1 antibody - ab96313 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab96313 stained PC12 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab96313 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Plexin D1 antibody - ab93234 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Plexin D1 antibody (ab93234) at 1 µg/ml + Brain (Mouse) Tissue Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PLXND1 / Plexin D1 Antibody (aa47-1271) - LS-C38286 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (aa1683-1694) - LS-C55297 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (aa47-1271, PE) - LS-C182933 from LifeSpan Bioscience

Prices $635.00
Sizes 100 tst
Host Goat
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (Extracellular Domain, Biotin) - LS-C74983 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (Tyr1642, APC) - LS-C281087 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (Tyr1642, AP) - LS-C281088 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (Tyr1642, Biotin) - LS-C281089 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (Tyr1642, FITC) - LS-C281090 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (Tyr1642, Azide-free, HRP) - LS-C281092 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (phospho-Tyr1642) - LS-C97104 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot of anti-Phospho-PLXND1-pY1642 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Anti-PLXND1 / Plexin D1 Antibody (Tyr1642, PE) - LS-C281091 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (phospho-Tyr1642) - LS-C328274 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXND1 / Plexin D1 Antibody (aa1633-1724) - LS-C185653 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of methanol-fixed HeLa using Plexin D1 antibody at 1:500 dilution.

Plexin D1 Antibody [Unconjugated] - AF4160 from Novus Biologicals

Prices $99.00, $365.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Recombinant Human Semaphorin 3E (Catalog # 3239-S3) inhibits proliferation in the HUVEC human umbilical vein endothelial cells in a dose-dependent manner (orange line). Plexin D1 mediated inhibition elicited by Recombinant Human Semaphorin 3E (5 ug/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human Plexin D1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4160). The ND50 is typically 0.5-2 ug/mL.

Plexin D1 Antibody - NB300-961 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Plexin D1 Antibody (752815) - MAB41601 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 752815
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line and IMR‑32 human neuroblastoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Plexin D1 Monoclonal Antibody (Catalog # MAB41601) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Plexin D1 at approximately 250 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Plexin D1 Antibody (752829) - MAB4160 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 752829
Search more