CDKN1C

Gene Symbol CDKN1C
Entrez Gene 1028
Alt Symbol BWCR, BWS, KIP2, WBS, p57, p57Kip2
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Other Description cyclin-dependent kinase inhibitor 1C|cyclin-dependent kinase inhibitor p57
Swissprots P49918
Accessions AAB05896 BAA11014 BAA11015 EAX02524 EAX02525 P49918 BC039188 BC067842 AAH67842 BM673714 CD676249 EU570054 ACB69757 U22398 AAA85095 XM_005252732 XP_005252789 XM_006725126 XP_006725189 NM_000076 NP_000067 NM_001122630 NP_001116102 NM_001122631 NP_001116103
Function Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. {ECO:0000269|PubMed:22634751}.
Top Pathways Cell cycle

p57 CRISPR/Cas9 KO Plasmid (h) - sc-400444 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 HDR Plasmid (h) - sc-400444-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 Double Nickase Plasmid (h) - sc-400444-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 Double Nickase Plasmid (h2) - sc-400444-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 CRISPR Activation Plasmid (h) - sc-400444-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 CRISPR Activation Plasmid (h2) - sc-400444-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 Lentiviral Activation Particles (h) - sc-400444-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 Lentiviral Activation Particles (h2) - sc-400444-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p57 siRNA (h) - sc-35751 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Kip 2 p57 shRNA Plasmid (h) - sc-35751-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Kip 2 p57 shRNA (h) Lentiviral Particles - sc-35751-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p57 Kip2 RNAi - H00001028-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN5862 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5862 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04155 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04155

CDKN1C siRNA (Human) - CRH0740 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDKN1C - MBS8225345 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human CDKN1C siRNA - orb261242 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDKN1C shRNA Plasmid (Human) - CHH0740 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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