CDKN1C

Gene Symbol	CDKN1C
Entrez Gene	1028
Alt Symbol	BWCR, BWS, KIP2, WBS, p57, p57Kip2
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Other Description	cyclin-dependent kinase inhibitor 1C|cyclin-dependent kinase inhibitor p57
Swissprots	P49918
Accessions	AAB05896 BAA11014 BAA11015 EAX02524 EAX02525 P49918 BC039188 BC067842 AAH67842 BM673714 CD676249 EU570054 ACB69757 U22398 AAA85095 XM_005252732 XP_005252789 XM_006725126 XP_006725189 NM_000076 NP_000067 NM_001122630 NP_001116102 NM_001122631 NP_001116103
Function	Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. {ECO:0000269|PubMed:22634751}.
Top Pathways	Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human p57 Kip2 peptide - ab95040 from Abcam Category Peptide

Human p57 Kip2 protein fragment - ab112270 from Abcam Category Protein Source Wheat germ Species Human

CDKN1C / p57 Kip2 Antibody Blocking Peptide - LS-E613 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDKN1C / p57 Kip2 Antibody Blocking Peptide - LS-E31325 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human p57 Kip2 Protein - H00001028-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CDKN1C-Antibody-N-term-Blocking-peptide - BP10945a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cdkn1c peptide - orb72513 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

CDKN1C Blocking Peptide - 33R-1025 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDKN1C / KIP2 - H00001028-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDKN1C / KIP2 - H00001028-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDKN1C / KIP2 (N-term) Control Peptide - AP55485CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CDKN1C Peptide - 7015P from ProSci Category Peptide Species Human

CDKN1C fusion protein - ag19849 from Proteintech Group Category Protein Species Human

CDKN1C fusion protein - Ag19927 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CDKN1C - CDKN1C-30575TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CDKN1C, His-tagged - CDKN1C-11061H from Creative Biomart Category Protein Source E.coli Species Human

p57 (S306) Peptide - BS1683P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p57 (D38) Peptide - BS9134P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cyclin-dependent kinase inhibitor 1C(CDKN1C) - CSB-YP005088HU CSB-EP005088HU CSB-BP005088HU CSB-MP005088HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

p57 Kip2 Blocking Peptide - CBP4371 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Rat

p57 Kip2 Blocking Peptide - abx161582 from Abbexa Category Peptide Species Human, Rat

p57 Kip2 Protein - NBP1-89917PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Cyclin-dependent kinase inhibitor 1C (CDKN1C), Recombinant Protein - MBS960510 from MyBioSource Category Protein Prices $1,075.00, $1,075.00, $1,305.00, $1,305.00, $1,685.00, $1,685.00, $2,150.00, $2,150.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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