TNFRSF10A

Gene Symbol TNFRSF10A
Entrez Gene 8797
Alt Symbol APO2, CD261, DR4, TRAILR-1, TRAILR1
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 10a
Other Description TNF-related apoptosis-inducing ligand receptor 1|TRAIL receptor 1|TRAIL-R1|cytotoxic TRAIL receptor|death receptor 4|tumor necrosis factor receptor superfamily member 10A|tumor necrosis factor receptor superfamily member 10a variant 2
Swissprots O00220 Q96E62 A8K5I4 Q53Y72
Accessions ABK41896 CCA94571 CCQ43238 EAW63636 O00220 AK291299 BAF83988 BC012866 AAH12866 BT006906 AAP35552 CN423254 DB101031 DQ891791 ABM82717 DQ894973 ABM85899 FJ795027 ACO37639 JF729355 AEB77762 U90875 AAC51226 NM_003844 NP_003835
Function Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. {ECO:0000269|PubMed:9430227}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells.
Top Pathways Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

DR4 (CD261) Human ELISA Kit - ab46510 from Abcam

Category ELISA Kit
Prices $489.00, $734.00
Sizes 1 x 96 tests, 2 x 96 tests
Sensitivity < 8 pg/ml
Range 31.25 pg/ml - 1000 pg/ml
Representative Standard Curve using ab46510

Human TNFRSF10A ELISA Kit - RAB0746 from Sigma-Aldrich

Category ELISA Kit
Prices $633.00
Sizes 1 kt

Mouse TNFRSF10A / DR4 ELISA Kit (Sandwich ELISA) - LS-F7088 from LifeSpan Bioscience

Category ELISA Kit
Prices $670.00
Sizes 1 plate
Sensitivity 0.056 ng/ml
Range 0.156-10 ng/ml

Human TNFRSF10A / DR4 ELISA Kit (Custom ELISA) - LS-F365 from LifeSpan Bioscience

Category ELISA Kit
Prices $670.00, $1,190.00, $2,570.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Human TNFRSF10A / DR4 ELISA Kit (Sandwich ELISA) - LS-F12841 from LifeSpan Bioscience

Category ELISA Kit
Prices $530.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

Tumor necrosis factor receptor superfamily member 10A, TNFRSF10A, Human, ELISA Kit - E8715h from ARP American Research Products

Category ELISA Kit
Prices $576.00
Sizes 96 t
Range 0.156-10 ng/mL

Tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Human, ELISA Kit - CSB-E04747h from ARP American Research Products

Category ELISA Kit
Prices $450.00, $595.00, $596.00, $599.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS072193 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS052236 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS064037 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

tumor necrosis factor receptor superfamily, member 10a, ELISA Kit - MBS704316 from MyBioSource

Category ELISA Kit
Prices $250.00, $435.00, $625.00, $2,595.00, $4,905.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Trail Receptor 1 (CD261) ELISA Kit - DEIA4826 from Creative Diagnostics

Category ELISA Kit
Sensitivity 8 pg/mL

TRAIL R1, ELISA Kit - MBS2502727 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/mL
Range 0.156-10ng/mL

TRAIL R1, ELISA Kit - MBS2515453 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/mL
Range 0.156-10ng/mL

TRAIL R1, ELISA Kit - MBS335465 from MyBioSource

Category ELISA Kit
Prices $305.00, $470.00, $675.00
Sizes 1x48 wells (Pre-Coated), 1x96 wells (Pre-Coated), 2x96 wells (Pre-Coated)
Sensitivity The sensitivity, minimum detectable dose of human TRAIL R1 using this TRAIL R1 ELISA kit was found to be <8pg/ml. This was determined by adding 3 standard deviations to the mean OD obtained when the zero standard was assayed 32 times.

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS100260 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS088532 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS081907 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Necrosis Factor Receptor Superfamily, Member 10A, ELISA Kit - MBS098043 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Necrosis Factor Receptor Superfamily, Member 10A (TNFRSF10A), ELISA Kit - MBS2020243 from MyBioSource

Category ELISA Kit
Prices $350.00, $525.00, $715.00, $2,915.00, $5,315.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.056ng/mL.
Range 0.156-10ng/mL

ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 10A (TNFRSF10A) - SEA136Mu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.056ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human tumor necrosis factor-related apoptosis-inducing ligand receptor 1(TRAIL-R1) ELISA Kit - CSB-E04747h from Cusabio

Category ELISA Kit
Sensitivity 0.078 ng/ml
Range 0.312 ng/ml-20 ng/ml

TRAIL-R1(Tumor Necrosis Factor Related Apoptosis Inducing Ligand 1) ELISA Kit - E-EL-R1038 from Iwai North America Inc.

Category ELISA Kit
Prices $580.00
Sizes 1 kit
Sensitivity 0.1 ng/mL
Range 0.16~10 ng/mL

Human TRAIL-R1 ELISA Kit - abx054917 from Abbexa

Category ELISA Kit
Sensitivity 22 pg/ml
Range 80 pg/ml - 4000 pg/ml

Human Tumor necrosis factor receptor superfamily member 10A ELISA Kit - abx253650 from Abbexa

Category ELISA Kit
Range 0.156 ng/ml - 10 ng/ml
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