EPHX1

Gene Symbol EPHX1
Entrez Gene 2052
Alt Symbol EPHX, EPOX, HYL1, MEH
Species Human
Gene Type protein-coding
Description epoxide hydrolase 1, microsomal (xenobiotic)
Other Description epoxide hydratase|epoxide hydrolase 1
Swissprots Q9NPE7 Q9NQU6 P07099 Q5VTJ6 Q9NQV0 B2R8N0 Q9NQU7 Q9NP75 Q9NQU8 Q9NQV2 Q9NQU9 Q9NQV1
Accessions AAB60649 AAC41694 AAF87726 AAF87727 AAF87728 AAF87729 AAF87730 AAF87731 AAF87732 AAF87733 AAF87734 AAF87735 AAF87736 AAF87737 AAF87738 AAX81410 EAW69754 EAW69755 EAW69756 EAW69757 P07099 AK313436 BAG36227 BC003567 AAH03567 BC008291 AAH08291 BC095430 AAH95430 BJ994650 BU541640 CR541963 CAG46761 DQ892506 ABM83432 DQ895720 ABM86646 HY180507 J03518 AAA61305 KF032815 AGL94507 L25878 AAA52389 L25879 AAA52390 M36374 AAA59580 U34722 X07936 CAA30759 Y00424 CAA68486 NM_000120 NP_000111 NM_001136018 NP_001129490 NM_001291163 NP_001278092
Function Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
Subcellular Location Microsome membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Found in liver. {ECO:0000269|PubMed:12878321}.
Top Pathways Bile secretion, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450

mEH (H-300) - sc-22748 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
mEH (H-300): sc-22748. Western blot analysis of mEH expression in Hep G2 whole cell lysate.

mEH (D-16) - sc-22336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
mEH (D-16): sc-22336. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

mEH (17) - sc-135984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
mEH (17): sc-135984. Western blot analysis of mEH expression in WI 38 whole cell lysate.

Anti-Epoxide hydrolase antibody - ab88585 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Epoxide hydrolase antibody (ab88585) at 1 µg/ml + human liver tissue lysate at 50 µg

Anti-Epoxide hydrolase antibody [15B2AD9] - ab110307 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 15B2AD9
Overlay histogram showing HepG2 cells stained with ab110307 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab110307, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody - LS-C65485 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Goat
Clonality Polyclonal

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (clone AT2E5) - LS-C103479 from LifeSpan Bioscience

Prices $255.00, $315.00
Sizes 50 µl, 100 µl
Host Mouse
Clonality Monoclonal
Clone AT2E5

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa182-231) - LS-C81831 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa35-84) - LS-C116568 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EPHX1 antibody LS-C116568 Western blot of Jurkat lysate.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody - LS-C307407 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody - LS-C311112 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (clone 2E7) - LS-C197149 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E7
Detection limit for recombinant GST tagged EPHX1 is approximately 3 ng/ml as a capture antibody.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody - LS-C192763 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of various cell lines, using EPHX1 antibody.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (clone 2C1) - LS-C175279 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EPHX1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EPHX1.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa1-223) - LS-C186064 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded SG xenograft using Epoxide hydrolase 1 antibody at 1:500 dilution.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa14-292) - LS-C186125 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded SG xenograft using Epoxide hydrolase 1 antibody at 1:100 dilution.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (clone 3A10) - LS-C175275 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A10
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-EPHX1 mouse monoclonal antibody.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody - LS-C335199 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human esophageal cancer using EPHX1 antibody at dilution of 1:100 (200x lens).

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (clone 3F10) - LS-C175278 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3F10
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-EPHX1 mouse monoclonal antibody.

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa21-230, clone 2D8) - LS-C336974 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D8
IHC of paraffin-embedded Human pancreas tissue using anti-EPHX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa21-230, clone 4G4) - LS-C336965 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4G4
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-EPHX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-EPHX1 / Epoxide Hydrolase 1 Antibody (aa21-230, clone 3F11) - LS-C336966 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3F11
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-EPHX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

EPHX1 Antibody - NBP1-32882 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EPHX1 Antibody [NBP1-32882] - Sample (30 ug of whole cell lysate) A: H1299 B: Hela 10% SDS PAGE; antibody diluted at 1:1000.

EPHX1 Antibody - NBP1-33011 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EPHX1 Antibody [NBP1-33011] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.

EPHX1 Antibody - H00002052-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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