Gene Symbol | EPHX1 |
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Entrez Gene | 2052 |
Alt Symbol | EPHX, EPOX, HYL1, MEH |
Species | Human |
Gene Type | protein-coding |
Description | epoxide hydrolase 1, microsomal (xenobiotic) |
Other Description | epoxide hydratase|epoxide hydrolase 1 |
Swissprots | Q9NPE7 Q9NQU6 P07099 Q5VTJ6 Q9NQV0 B2R8N0 Q9NQU7 Q9NP75 Q9NQU8 Q9NQV2 Q9NQU9 Q9NQV1 |
Accessions | AAB60649 AAC41694 AAF87726 AAF87727 AAF87728 AAF87729 AAF87730 AAF87731 AAF87732 AAF87733 AAF87734 AAF87735 AAF87736 AAF87737 AAF87738 AAX81410 EAW69754 EAW69755 EAW69756 EAW69757 P07099 AK313436 BAG36227 BC003567 AAH03567 BC008291 AAH08291 BC095430 AAH95430 BJ994650 BU541640 CR541963 CAG46761 DQ892506 ABM83432 DQ895720 ABM86646 HY180507 J03518 AAA61305 KF032815 AGL94507 L25878 AAA52389 L25879 AAA52390 M36374 AAA59580 U34722 X07936 CAA30759 Y00424 CAA68486 NM_000120 NP_000111 NM_001136018 NP_001129490 NM_001291163 NP_001278092 |
Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. |
Subcellular Location | Microsome membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Found in liver. {ECO:0000269|PubMed:12878321}. |
Top Pathways | Bile secretion, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450 |
Human Epoxide hydrolase full length protein - ab114694 from Abcam
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Human Epoxide hydrolase protein fragment - ab152366 from Abcam
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Human Epoxide hydrolase protein fragment - ab177622 from Abcam
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EPHX1 / Epoxide Hydrolase 1 Antibody Blocking Peptide - LS-E19528 from LifeSpan Bioscience
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EPHX1 / Epoxide Hydrolase 1 Antibody Blocking Peptide - LS-E19529 from LifeSpan Bioscience
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EPHX1 Recombinant Protein - H00002052-P01 from Novus Biologicals
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EPHX1 Partial Recombinant Protein - H00002052-Q01 from Novus Biologicals
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EPHX1-Antibody-N-term-Blocking-peptide - BP12223a from Abgent, a WuXi AppTec company
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EPHX1 Recombinant Protein - GTX48207-PRO from GeneTex
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Human EPHX1 protein - orb244185 from Biorbyt
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EPHX1 Blocking Peptide - 33R-1773 from Fitzgerald
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EPHX1 Blocking Peptide - 33R-3472 from Fitzgerald
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EPHX1 protein (T7 tag) - 80R-3693 from Fitzgerald
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Epoxide hydrolase 1 / EPHX1 (T7 tag) - AR51380PU-N from Acris Antibodies
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Epoxide hydrolase 1 / EPHX1 (T7 tag) - AR51380PU-S from Acris Antibodies
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Epoxide hydrolase 1 / EPHX1 - H00002052-P01-10 from Acris Antibodies
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Epoxide hydrolase 1 / EPHX1 - H00002052-P01-25 from Acris Antibodies
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Epoxide hydrolase 1 / EPHX1 - H00002052-Q01-10 from Acris Antibodies
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Epoxide hydrolase 1 / EPHX1 - H00002052-Q01-25 from Acris Antibodies
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EPHX1, 21- 455aa Human, T7-tagged, E.coli - 01-P2560 from ARP American Research Products
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EPHX1 Recombinant Protein - XW-RP3078 from ProSci
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EPHX1 fusion protein - ag7443 from Proteintech Group
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EPHX1 fusion protein - Ag7465 from Proteintech Group
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Recombinant Human EPHX1, MYC/DDK-tagged - EPHX1-390H from Creative Biomart
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Recombinant Human EPHX1, T7-tagged - EPHX1-392H from Creative Biomart
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