SNRPE

Gene Symbol	SNRPE
Entrez Gene	6635
Alt Symbol	B-raf, HYPT11, SME, Sm-E
Species	Human
Gene Type	protein-coding
Description	small nuclear ribonucleoprotein polypeptide E
Other Description	sm protein E|small nuclear ribonucleoprotein E|snRNP-E
Swissprots	B2R5B9 Q5BKT2 P62304
Accessions	AAB59365 EAW91494 EAW91495 P62304 AI263891 AK307255 AK309140 AK312130 BAG35066 BC002639 AAH02639 BC072433 BC090951 AAH90951 D28435 BAA05801 DW441956 M15919 AAA36621 M37716 AAA90926 X12466 CAA31007 NM_001304464 NP_001291393 NM_003094 NP_003085 NR_130746
Function	Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23246290, ECO:0000269|PubMed:23333303}.
Subcellular Location	Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Tissue Specificity	Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis. {ECO:0000269|PubMed:23246290}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNRPE full length protein - ab104036 from Abcam Category Protein Source E. coli Species Human

SNRPE Antibody Blocking Peptide - LS-E23052 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNRPE Antibody Blocking Peptide - LS-E23051 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SNRPE Protein - H00006635-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SNRPE-Antibody-Center-Blocking-peptide - BP10713c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SNRPE protein - orb169329 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Source E. coli

SNRPE protein (His tag) - 80R-1677 from Fitzgerald Category Protein Prices $255.00 Sizes 10 µg Source E.coli

B-RAF Blocking Peptide - abx062302 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Dog, Monkey

B-RAF Blocking Peptide - abx062043 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Zebrafish

SNRPE (1-92, His-tag) - AR09859PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

SNRPE (1-92, His-tag) - AR09859PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

SNRPE - H00006635-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

Small Nuclear Ribonucleoprotein Polypeptide E, Human Recombinant - 228-12860-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide E - 228-12860-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide E - 228-12860-3 from RayBiotech Category Protein Prices $1,448.00 Sizes 3 µg Source Escherichia Coli. Species Human

SNRPE, 1-92aa, Human, His tag, E.coli - 01-SNRP-E from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

SNRPE fusion protein - Ag14227 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SNRPE fusion protein - Ag16948 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human SNRPE protein - BP002068-PRO-104 from Syd Labs Category Protein Prices $160.00, $1,200.00 Sizes 5 µg, 50 µg Source E. Coli-derived. Species Human

Recombinant B-RAF protein - 31161 from ActiveMotif Category Protein Prices $390.00 Sizes 10 µg Source Baculovirus Species Human

SNRPE, 1-92aa, Recombinant Protein - GWB-P1119A from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 10 μg, 50 μg Source E.coli Species Human

SNRPE Human Protein - GWB-BSP665 from Genway Biotech Category Protein Prices $75.00, $165.00, $1,435.00 Sizes 1 μg, 5 μg, 50 μg Source Escherichia Coli. Species Human

b-RAF (GST) Human Recombinant Protein - GWB-4E9DD2 from Genway Biotech Category Protein Prices $410.00 Sizes 10 µg Species Human

Recombinant Human SNRPE, His-tagged - SNRPE-30584TH from Creative Biomart Category Protein Source E. coli

Recombinant Human SNRPE, GST-tagged - SNRPE-2850H from Creative Biomart Category Protein Source E.coli Species Human

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