SNRPE

Gene Symbol SNRPE
Entrez Gene 6635
Alt Symbol B-raf, HYPT11, SME, Sm-E
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein polypeptide E
Other Description sm protein E|small nuclear ribonucleoprotein E|snRNP-E
Swissprots B2R5B9 Q5BKT2 P62304
Accessions AAB59365 EAW91494 EAW91495 P62304 AI263891 AK307255 AK309140 AK312130 BAG35066 BC002639 AAH02639 BC072433 BC090951 AAH90951 D28435 BAA05801 DW441956 M15919 AAA36621 M37716 AAA90926 X12466 CAA31007 NM_001304464 NP_001291393 NM_003094 NP_003085 NR_130746
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23246290, ECO:0000269|PubMed:23333303}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Tissue Specificity Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis. {ECO:0000269|PubMed:23246290}.
Top Pathways Spliceosome

Sm E CRISPR/Cas9 KO Plasmid (h) - sc-418612 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E HDR Plasmid (h) - sc-418612-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E Double Nickase Plasmid (h) - sc-418612-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E Double Nickase Plasmid (h2) - sc-418612-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E CRISPR Activation Plasmid (h) - sc-418612-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E CRISPR Activation Plasmid (h2) - sc-418612-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E Lentiviral Activation Particles (h) - sc-418612-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E Lentiviral Activation Particles (h2) - sc-418612-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sm E siRNA (h) - sc-38329 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sm E shRNA Plasmid (h) - sc-38329-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sm E shRNA (h) Lentiviral Particles - sc-38329-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNRPE RNAi - H00006635-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN20274 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20274 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08788 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08788

SNRPE siRNA (Human) - CRH4517 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNRPE - MBS828784 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SNRPE(NM_003094.2) - SHL022332 from Creative biogene

Category siRNA
Species Reactivities Human

Human SNRPE siRNA - orb265019 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNRPE shRNA Plasmid (Human) - CHH4517 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SNRPE miRNA 3'UTR clone - MiUTR1H-09701 from Creative biogene

Species Reactivities Human
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