GPHN

Gene Symbol	GPHN
Entrez Gene	10243
Alt Symbol	GEPH, GPH, GPHRYN, HKPX1, MOCODC
Species	Human
Gene Type	protein-coding
Description	gephyrin
Other Description	-
Swissprots	Q9NQX3 Q9P2G2 Q9H4E9
Accessions	EAW80923 EAW80924 EAW80925 EAW80926 Q9NQX3 AB037806 BAA92623 AF272663 AAF81785 AJ272033 CAC81240 AJ272343 CAC10537 AK025169 AK294532 BAH11801 AK295577 BAH12110 AK297447 BAH12583 AK315569 BAG37944 BC030016 AAH30016 BQ575870 DQ892463 ABM83389 DQ895675 ABM86601 XM_005267254 XP_005267311 XM_011536340 XP_011534642 XM_011536342 XP_011534644 XM_011536343 XP_011534645 XM_011536344 XP_011534646 XM_011536345 XP_011534647 XM_011536346 XP_011534648 XM_011536347 XP_011534649 XM_011536348 XP_011534650 XM_011536349 XP_011534651 NM_001024218 NP_001019389 NM_020806 NP_065857
Function	Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. {ECO:0000250}.
Subcellular Location	Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Cytoplasmic face of glycinergic postsynaptic membranes. {ECO:0000250}.
Top Pathways	GABAergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Gephyrin CRISPR/Cas9 KO Plasmid (h) - sc-401197 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin HDR Plasmid (h) - sc-401197-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin Double Nickase Plasmid (h) - sc-401197-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin Double Nickase Plasmid (h2) - sc-401197-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin CRISPR Activation Plasmid (h) - sc-401197-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin CRISPR Activation Plasmid (h2) - sc-401197-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin Lentiviral Activation Particles (h) - sc-401197-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin Lentiviral Activation Particles (h2) - sc-401197-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gephyrin siRNA (h) - sc-35464 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Gephyrin shRNA Plasmid (h) - sc-35464-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Gephyrin shRNA (h) Lentiviral Particles - sc-35464-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Gephyrin/GPHN RNAi - H00010243-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Gephyrin/GPHN RNAi - H00010243-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU076171 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9527 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9527 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

GPHN siRNA (Human) - CRH6930 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GPHN - MBS8223921 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human GPHN (NM_020806.4) - SHH305886 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GPHN(NM_001024218.1) - SHH096347 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GPHN(NM_020806.4) - SHH096365 from Creative biogene Category siRNA Species Reactivities Human

GPHN shRNA Plasmid (Human) - CHH6930 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

GPHN miRNA 3'UTR clone - MiUTR1H-04163 from Creative biogene Species Reactivities Human

GPHN miRNA 3'UTR clone - MiUTR1H-04164 from Creative biogene Species Reactivities Human

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