SMPD1

Gene Symbol SMPD1
Entrez Gene 6609
Alt Symbol ASM, ASMASE, NPD
Species Human
Gene Type protein-coding
Description sphingomyelin phosphodiesterase 1, acid lysosomal
Other Description acid sphingomyelinase|sphingomyelin phosphodiesterase
Swissprots Q16837 A8K8M3 Q16841 P17406 E9PKS3 P17405 Q13811
Accessions AAA58378 AAA75008 AAA75009 AAL79527 CAA45145 CDM61370 EAW68726 EAW68727 EAW68728 EAW68729 P17405 AA746054 AB209775 BAD93012 AK292388 BAF85077 AY649987 AAV68198 BC041164 AAH41164 BI599208 BM686561 BU845962 HQ132745 ADW08999 HQ132746 ADW09000 HQ132747 ADW09001 HQ132748 ADW09002 M59916 AAA58377 X52678 CAA36901 X52679 CAA36902 X59960 CAA42584 XM_005253075 XP_005253132 XM_011520303 XP_011518605 XM_011520304 XP_011518606 XR_930886 NM_000543 NP_000534 NM_001007593 NP_001007594 NR_027400
Function Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.
Subcellular Location Lysosome.
Top Pathways Lysosome, Sphingolipid signaling pathway, Sphingolipid metabolism

Acidic Sphingomyelinase Assay Kit (Fluorimetric) - ab190554 from Abcam

Category Cellular Assay
Prices $369.00
Sizes 200 tests
Sensitivity 1 U/ml

Sphingomyelinase Assay Kit (Colorimetric) - ab138876 from Abcam

Category Cellular Assay
Prices $278.00
Sizes 200 tests
Sensitivity 0.08 mU/ml
Sphingomyelinase dose response was measured on a 96-well plate with ab138876 using a microplate reader. As low as 0.08 mU/ml sphingomyelinase can be detected with 60 minutes incubation (n=3).

Human SMPD1 / Acid Sphingomyelinase ELISA Kit (Sandwich ELISA) - LS-F4573 from LifeSpan Bioscience

Category ELISA Kit
Prices $690.00
Sizes 1 plate
Sensitivity 0.057 ng/ml
Range 0.156-10 ng/ml

Human SMPD1 / Acid Sphingomyelinase ELISA Kit (Sandwich ELISA) - LS-F10889 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.78
Range 0.156-10 ng/ml

Human Acid Sphingomyelinase ELISA Kit - abx150523 from Abbexa

Category ELISA Kit
Sensitivity 0.073 ng/ml
Range 0.156 ng/ml - 10 ng/ml

Human Acid Sphingomyelinase ELISA Kit - abx052984 from Abbexa

Category ELISA Kit
Sensitivity 18 pg/ml
Range 45 pg/ml - 2000 pg/ml

Acid Sphingomyelinase (ASM), Human, ELISA Kit - SEB360Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 0.123ng/mL
Range 0.312-20ng/mL

Acid sphingomyelinase, ASM, Human, ELISA Kit - CSB-E09361h from ARP American Research Products

Category ELISA Kit
Prices $550.00, $790.00, $791.00, $794.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 0.3 ng/ml
Range 1.25 ng/ml-80 ng/ml

Acid Sphingomyelinase, Human, ELISA Kit - E01A0620 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 1.0-25ng/mL,

Acid Sphingomyelinase, ASM, Human, ELISA Kit - E-EL-H0511 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Sphingomyelin phosphodiesterase, SMPD1, Human, ELISA Kit - E1360h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 0.78-50 ng/mL

Acid Sphingomyelinase, ASM, Rabbit, ELISA Kit - E-EL-RB1975 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Acid Sphingomyelinase, ASM, Chicken, ELISA Kit - E-EL-Ch2144 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Acid Sphingomyelinase, ASM, Porcine, ELISA Kit - E-EL-P2096 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Acid Sphingomyelinase, ASM, Sheep, ELISA Kit - E-EL-S0505 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

Acid Sphingomyelinase, ASM, Monkey, ELISA Kit - E-EL-MK1849 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Human ASM ELISA Kit - HA0627 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine ASM ELISA Kit - AA0627 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Human ASM(Acid Sphingomyelinase) ELISA Kit - E-EL-H0511 from Elabscience

Category ELISA Kit
Sensitivity 0.19 ng/mL
Range 0.31—20 ng/mL

Human ASM (Acid Sphingomyelinase) CLIA Kit - E-CL-H0415 from Elabscience

Category CLIA Kit
Sensitivity 46.88 pg/mL
Range Average Recovery (%)

Acid Sphingomyelinase, ELISA Kit - MBS726278 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL

Acid Sphingomyelinase, ELISA Kit - MBS049424 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acid Sphingomyelinase, ELISA Kit - MBS012564 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acid Sphingomyelinase, ELISA Kit - MBS032540 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acid Sphingomyelinase, ELISA Kit - MBS044831 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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