SMPD1

Gene Symbol	SMPD1
Entrez Gene	6609
Alt Symbol	ASM, ASMASE, NPD
Species	Human
Gene Type	protein-coding
Description	sphingomyelin phosphodiesterase 1, acid lysosomal
Other Description	acid sphingomyelinase|sphingomyelin phosphodiesterase
Swissprots	Q16837 A8K8M3 Q16841 P17406 E9PKS3 P17405 Q13811
Accessions	AAA58378 AAA75008 AAA75009 AAL79527 CAA45145 CDM61370 EAW68726 EAW68727 EAW68728 EAW68729 P17405 AA746054 AB209775 BAD93012 AK292388 BAF85077 AY649987 AAV68198 BC041164 AAH41164 BI599208 BM686561 BU845962 HQ132745 ADW08999 HQ132746 ADW09000 HQ132747 ADW09001 HQ132748 ADW09002 M59916 AAA58377 X52678 CAA36901 X52679 CAA36902 X59960 CAA42584 XM_005253075 XP_005253132 XM_011520303 XP_011518605 XM_011520304 XP_011518606 XR_930886 NM_000543 NP_000534 NM_001007593 NP_001007594 NR_027400
Function	Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.
Subcellular Location	Lysosome.
Top Pathways	Lysosome, Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Acid sphingomyelinase full length protein - ab132844 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Acid sphingomyelinase protein fragment - ab114465 from Abcam Category Protein Prices $420.00 Sizes 2 µg Source Wheat germ Species Human

SMPD1 / Acid Sphingomyelinase Antibody Blocking Peptide - LS-E1506 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMPD1 Recombinant Protein - H00006609-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SMPD1-Antibody-C-term-Blocking-peptide - BP12227b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SMPD1-Antibody-C-term-Blocking-Peptide - BP8882b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human SMPD1, CF - 5348-PD-010 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, His62-Pro628, with a C-terminal 10-His tag

Human SMPD1 His tag protein - orb83439 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 10 μg, 20 μg Source Insect Species Human

Human SMPD1 His tag protein - orb83368 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Insect Species Human

SMPD1 Blocking Peptide - 33R-4082 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Acid Sphingomyelinase Blocking Peptide - abx063278 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Sheep

Human Acid Sphingomyelinase Protein - abx065097 from Abbexa Category Protein Source E.coli Species Human

SMPD1 - H00006609-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SMPD1 - H00006609-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SMPD1 - H00006609-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

SMPD1,ASM fusion protein - ag6180 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human ASM, His-tagged - ASM-3068H from Creative Biomart Category Protein Source E. Coli Species Human

Recombinant Human SMPD1, His tagged - SMPD1-655H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human SMPD1, His tagged - SMPD1-656H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human SMPD1 - SMPD1-26292TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Acid Sphingomyelinase (ASM) - RPB360Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Human SMPD1 / ASM Protein (His Tag) - 11087-H08B-10 from Sino Biological Category Protein Prices $178.00, $178.00 Sizes 10 µg, 20 µg Source Baculovirus-Insect Cells Species Human

Human SMPD1 / ASM Protein (His Tag) - 11087-H07B-10 from Sino Biological Category Protein Prices $178.00, $178.00 Sizes 10 µg, 20 µg Source Baculovirus-Insect Cells Species Human

Sphingomyelinase, Staphylococcus aureus - 567707 from EMD Millipore

Acid Sphingomyelinase Blocking Peptide - CBP2084 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Sheep

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