Gene Symbol | LRRFIP2 |
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Entrez Gene | 9209 |
Alt Symbol | HUFI-2 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat (in FLII) interacting protein 2 |
Other Description | LRR FLII-interacting protein 2|leucine-rich repeat flightless-interacting protein 2 |
Swissprots | Q9NXH5 B4DY63 A8MXR0 A8K649 Q68CV3 Q9Y608 |
Accessions | EAW64486 EAW64487 EAW64488 EAW64489 EAW64490 EAW64491 Q9Y608 AF115509 AAD41257 AK000255 BAA91035 AK024692 AK026336 AK124432 AK291514 BAF84203 AK302282 BAG63625 BC053668 AAH53668 BX648794 CR749705 CAH18481 DB033703 DC336346 R27776 XM_005265538 XP_005265595 XM_005265539 XP_005265596 XM_005265540 XP_005265597 XM_005265550 XP_005265607 XM_005265551 XP_005265608 XM_005265553 XP_005265610 XM_005265554 XP_005265611 XM_005265555 XP_005265612 XM_005265556 XP_005265613 XM_005265557 XP_005265614 XM_006713385 XP_006713448 XM_006713386 XP_006713449 XM_006713387 XP_006713450 XM_006713388 XP_006713451 XM_006713389 XP_006713452 XM_006713390 XP_006713453 XM_006713392 XP_006713455 XM_006713393 XP_006713456 XM_006713394 XP_006713457 XM_006713395 XP_006713458 XM_006713396 XP_006713459 XM_006713397 XP_006713460 XM_006713399 XP_006713462 XM_006713400 XP_006713463 XM_006713402 XP_006713465 XM_006713403 XP_006713466 XM_006713404 XP_006713467 XM_011534217 XP_011532519 XM_011534218 XP_011532520 XM_011534219 XP_011532521 XM_011534220 XP_011532522 XM_011534221 XP_011532523 XM_011534222 XP_011532524 XM_011534223 XP_011532525 XM_011534224 XP_011532526 XM_011534225 XP_011532527 XM_011534226 XP_011532528 XM_011534227 XP_011532529 XM_011534228 XP_011532530 XM_011534229 XP_011532531 NM_001134369 NP_001127841 NM_001282691 NP_001269620 NM_006309 NP_006300 NM_017724 NP_060194 |
Function | May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta- catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. {ECO:0000269|PubMed:15677333, ECO:0000269|PubMed:19265123}. |
Tissue Specificity | Widely expressed, with highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:10366446}. |
LRRFIP2 (C-14) - sc-100024 from Santa Cruz Biotechnology
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LRRFIP2 (D-17) - sc-100025 from Santa Cruz Biotechnology
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LRRFIP2 (H-58) - sc-368986 from Santa Cruz Biotechnology
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Anti-LRRFIP2 antibody - ab113293 from Abcam
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Anti-LRRFIP2 antibody - ab128290 from Abcam
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Anti-LRRFIP2 antibody [377C3a] - ab84874 from Abcam
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Anti-HUFI-2 / LRRFIP2 Antibody (N-Terminus) - LS-C125888 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (aa51-100) - LS-C116870 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (clone 377C3a) - LS-C184763 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus, AP) - LS-C262271 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (aa585-634) - LS-C151352 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus, APC) - LS-C262272 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus, Biotin) - LS-C262273 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus, FITC) - LS-C262274 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus, Azide-free, HRP) - LS-C262275 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (aa66-115) - LS-C146145 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus, PE) - LS-C262276 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody - LS-C308817 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus) - LS-C329785 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (aa150-200) - LS-C148719 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (clone 377C3a) - LS-C342788 from LifeSpan Bioscience
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Anti-HUFI-2 / LRRFIP2 Antibody (C-Terminus) - LS-C144340 from LifeSpan Bioscience
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LRRFIP2 Antibody - NBP2-27199 from Novus Biologicals
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LRRFIP2 Antibody - NBP1-76546 from Novus Biologicals
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LRRFIP2 Antibody - NBP1-83147 from Novus Biologicals
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