Gene Symbol | CRIM1 |
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Entrez Gene | 51232 |
Alt Symbol | CRIM-1, S52 |
Species | Human |
Gene Type | protein-coding |
Description | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
Other Description | cysteine-rich motor neuron 1 protein|cysteine-rich repeat-containing protein S52 |
Swissprots | Q2M2G4 Q7LCQ5 Q9H318 Q9NZV1 Q59GH0 |
Accessions | AAG37011 AAX88862 AAY14649 AAY14679 EAX00426 Q9NZV1 AB209139 BAD92376 AF167706 AAF34409 AK026159 AK300817 BAG62472 AY358371 AAQ88737 BC026227 BC111989 AAI11990 BC113371 AAI13372 BX648755 CR627451 XM_005264357 XP_005264414 XM_011532898 XP_011531200 XM_011532899 XP_011531201 XM_011532900 XP_011531202 XM_011532901 XP_011531203 XR_939687 NM_016441 NP_057525 |
Function | May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. {ECO:0000269|PubMed:12464430, ECO:0000269|PubMed:12805376}. |
Subcellular Location | Processed cysteine-rich motor neuron 1 protein: Secreted. |
Tissue Specificity | Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level). {ECO:0000269|PubMed:10642437, ECO:0000269|PubMed:12464430}. |
CRIM1 (G-17) - sc-167544 from Santa Cruz Biotechnology
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CRIM1 (Q-15) - sc-167546 from Santa Cruz Biotechnology
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CRIM1 (CREX-2) - sc-73860 from Santa Cruz Biotechnology
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Anti-CRIM1 antibody - ab57327 from Abcam
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Anti-CRIM1 antibody [MM0202-16G1] - ab89293 from Abcam
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Anti-CRIM1 antibody - C-terminal - ab189203 from Abcam
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Anti-CRIM1 antibody - C-terminal - ab135326 from Abcam
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Anti-CRIM1 Antibody (C-Terminus) IHC-plus™ - LS-B8848 from LifeSpan Bioscience
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Anti-CRIM1 Antibody (clone 6E4) IHC-plus™ - LS-B4525 from LifeSpan Bioscience
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Anti-CRIM1 Antibody (aa36-146, Azide-free) - LS-C327125 from LifeSpan Bioscience
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Anti-CRIM1 Antibody (aa961-1010) - LS-C151878 from LifeSpan Bioscience
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CRIM1 Antibody - AF1917 from Novus Biologicals
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CRIM1 Antibody - NBP1-80799 from Novus Biologicals
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CRIM1 Antibody (MM0202-16G1) - NBP2-12207 from Novus Biologicals
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CRIM1 Antibody - H00051232-A01 from Novus Biologicals
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CRIM1 Antibody [Biotin] - BAF1917 from Novus Biologicals
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Monoclonal Anti-CRIM1 antibody produced in mouse - WH0051232M1 from Sigma-Aldrich
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Anti-CRIM1 antibody produced in rabbit - SAB3500847 from Sigma-Aldrich
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Anti-CRIM1 antibody produced in rabbit - HPA000556 from Sigma-Aldrich
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CRIM1 Antibody (OALA04256) - OALA04256 from Aviva Systems Biology
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CRIM1 Antibody - C-terminal region (ARP65069_P050) - ARP65069_P050 from Aviva Systems Biology
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CRIM1-Antibody-monoclonal-M01 - AT1623a from Abgent, a WuXi AppTec company
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CRIM1 antibody [16G1] - GTX52655 from GeneTex
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Human CRIM1 Antibody - MAB1917 from R&D Systems
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Human CRIM1 MAb (Clone 253511), Mouse IgG1 - MAB1917-SP from R&D Systems
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