| Gene Symbol |
CRIM1
|
| Entrez Gene |
51232
|
| Alt Symbol |
CRIM-1, S52
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cysteine rich transmembrane BMP regulator 1 (chordin-like)
|
| Other Description |
cysteine-rich motor neuron 1 protein|cysteine-rich repeat-containing protein S52
|
| Swissprots |
Q2M2G4 Q7LCQ5 Q9H318 Q9NZV1 Q59GH0
|
| Accessions |
AAG37011 AAX88862 AAY14649 AAY14679 EAX00426 Q9NZV1 AB209139 BAD92376 AF167706 AAF34409 AK026159 AK300817 BAG62472 AY358371 AAQ88737 BC026227 BC111989 AAI11990 BC113371 AAI13372 BX648755 CR627451 XM_005264357 XP_005264414 XM_011532898 XP_011531200 XM_011532899 XP_011531201 XM_011532900 XP_011531202 XM_011532901 XP_011531203 XR_939687 NM_016441 NP_057525
|
| Function |
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. {ECO:0000269|PubMed:12464430, ECO:0000269|PubMed:12805376}.
|
| Subcellular Location |
Processed cysteine-rich motor neuron 1 protein: Secreted.
|
| Tissue Specificity |
Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level). {ECO:0000269|PubMed:10642437, ECO:0000269|PubMed:12464430}.
|