A2ML1

Gene Symbol	A2ML1
Entrez Gene	144568
Alt Symbol	CPAMD9
Species	Human
Gene Type	protein-coding
Description	alpha-2-macroglobulin-like 1
Other Description	C3 and PZP-like, alpha-2-macroglobulin domain containing 9|alpha-2-macroglobulin-like protein 1
Swissprots	B7Z7V4 Q96LQ8 Q6ZW52 F5H2Z2 Q8N1M4 A8K2U0 Q2M224 Q6ZW53 D3DUV3 B5MDD1
Accessions	A8K2U0 EAW88602 EAW88603 EAW88604 EAW88605 EAW88606 EAW88607 AK057908 BAB71612 AK096448 BAC04793 AK122624 BAC85494 AK123591 BAC85653 AK123592 BAC85654 AK123601 BAG53918 AK290355 BAF83044 AK302555 BAH13740 AL832139 AL832750 AL833479 BC093840 AAH93840 BC112131 AAI12132 BC172370 AAI72370 BF330285 BF354222 BX647674 BX648231 DA436610 DA456454 DA461408 EL594621 XM_011520566 XP_011518868 XM_011520567 XP_011518869 XR_931275 NM_001282424 NP_001269353 NM_144670 NP_653271
Function	Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin, papain, thermolysin, subtilisin A and, to a lesser extent, elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases. {ECO:0000250|UniProtKB:P01023, ECO:0000269|PubMed:16298998}.
Subcellular Location	Secreted {ECO:0000269|PubMed:16298998}.
Tissue Specificity	In the epidermis, expressed predominantly in the granular layer at the apical edge of keratinocytes (at protein level). Also detected in placenta, testis and thymus but not in epithelia of kidney, lung, small intestine or colon. {ECO:0000269|PubMed:16298998}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human A2ML1 ELISA Kit (Sandwich ELISA) - LS-F4892 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.27 ng/ml Range 0.781-50 ng/ml

Human a2ML1 ELISA Kit - abx150490 from Abbexa Category ELISA Kit Sensitivity 0.067 ng/ml Range 0.156 ng/ml - 10 ng/ml

Alpha-2-macroglobulin-like protein 1 (A2ML1), Human, ELISA Kit - CSB-EL001005HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 2.34 ng/ml Range 9.38 ng/ml-600 ng/ml

Alpha-2-Microglobulin Like Protein 1 (a2ML1), Human, ELISA Kit - SEA965Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.067ng/mL Range 0.156-10ng/mL

Alpha 2 macroglobulin like protein 1 (A2ML1), ELISA Kit - MBS7233648 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha 2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7237819 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-Macroglobulin Like Protein 1 (a2ML1), ELISA Kit - MBS2019526 from MyBioSource Category ELISA Kit Prices $345.00, $515.00, $695.00, $2,840.00, $5,180.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.27ng/mL. Range 0.781-50ng/mL

alpha-2-macroglobulin-like 1, ELISA Kit - MBS941123 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 2.34 ng/ml Range 9.38 ng/ml-600 ng/ml

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7241754 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7206692 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7211842 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7212106 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7240297 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7235952 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7240054 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7221413 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7233962 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-macroglobulin-like protein 1 (A2ML1), ELISA Kit - MBS7203000 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-2-Microglobulin Like Protein 1 (a2ML1), ELISA Kit - MBS9309476 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Alpha-2-Macroglobulin Like Protein 1 (a2ML1) - SEA965Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Alpha-2-macroglobulin-like protein 1(A2ML1) ELISA kit - CSB-EL001005HU from Cusabio Category ELISA Kit Sensitivity 2.34 ng/ml. Range 9.38 ng/ml-600 ng/ml

ELISA Kit for Alpha-2-Macroglobulin Like Protein 1 (a2ML1) - SEA965Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Alpha-2-Microglobulin Like Protein 1 (a2ML1), Human, ELISA Kit - DL-a2ML1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human a2ML1 ELISA Kit - abx570246 from Abbexa Category ELISA Kit Sensitivity 0.067 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human A2ML1 ELISA Kit - E001585 from Biobool Category ELISA Kit Sensitivity Typically less than 0.27ng/mL.

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