MCF2L

Gene Symbol	MCF2L
Entrez Gene	23263
Alt Symbol	ARHGEF14, DBS, OST
Species	Human
Gene Type	protein-coding
Description	MCF.2 cell line derived transforming sequence-like
Other Description	DBL's big sister|MCF2 transforming sequence-like protein|guanine nucleotide exchange factor DBS
Swissprots	A2A2X1 O15068 Q5VXT1 E9PDN8 Q8N679 Q765G9 B4DIL6 A2A3G8 Q765G8 B4DHD6 Q6ZWD4 A2A2X2 Q5JU56 A2A3G6
Accessions	EAX09175 EAX09176 EAX09177 EAX09178 EAX09179 EAX09180 O15068 AB002360 BAA20817 AB116074 BAD08351 AB116075 BAD08352 AF086413 AK022184 AK057899 BAB71611 AK092739 AK094768 BAG52925 AK123267 AK295047 BAG58097 AK295670 BAG58528 AK307867 AK315969 BAH14340 AW241629 BC011853 AAH11853 BC020208 AAH20208 BC107066 AAI07067 BC107067 AAI07068 BX648279 CR988747 DA114166 DA313448 DA769805 DB476653 DQ892041 ABM82967 DQ895233 ABM86159 EF212235 XM_005268309 XP_005268366 XM_005268314 XP_005268371 XM_005268316 XP_005268373 XM_011537482 XP_011535784 XM_011537483 XP_011535785 XM_011537484 XP_011535786 XM_011537485 XP_011535787 XM_011537486 XP_011535788 XM_011537487 XP_011535789 XM_011537488 XP_011535790 XM_011537489 XP_011535791 XM_011537490 XP_011535792 XM_011537491 XP_011535793 XM_011537492 XP_011535794 XM_011537493 XP_011535795 NM_001112732 NP_001106203 NM_024979 NP_079255
Function	Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42. {ECO:0000250, ECO:0000269|PubMed:15157669}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MCF2L / DBS Antibody Blocking Peptide - LS-E6163 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MCF2L Protein - H00023263-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MCF2L-Antibody-C-term-Blocking-Peptide - BP18793b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARHGEF14 Peptide - AC21-2838-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MCF2L - H00023263-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCF2L - H00023263-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MCF2L fusion protein - ag2223 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Dolichyl Diphosphooligosaccharide Protein Glycosyltransferase (DDOST) - RPJ279Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Low Density Lipoprotein Receptor Related Protein 2 (LRP2) - RPD101Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Guanine nucleotide exchange factor DBS(MCF2L) ,partial - CSB-YP521145HU CSB-EP521145HU CSB-BP521145HU CSB-MP521145HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MCF2L (transcript variant 2) - TP305825 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MCF2L, Peptide - MBS427912 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

MCF2L Protein - NBP1-88823PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MCF2L Peptide, Human - M34GP09307H from Creative Peptides Category Peptide Source Synthetic. Species Human

MCF2L fusion protein - Ag25906 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Guanine nucleotide exchange factor DBS (MCF2L), partial, Recombinant Protein - MBS1104125 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MCF2L fusion protein - Ag25917 from Proteintech Group Category Protein Source E. coli -derived, PET30a Species Human

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