SART3

Gene Symbol	SART3
Entrez Gene	9733
Alt Symbol	DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb)
Species	Human
Gene Type	protein-coding
Description	squamous cell carcinoma antigen recognized by T cells 3
Other Description	SART-3|hSART-3|p110 nuclear RNA-binding protein|squamous cell carcinoma antigen recognized by T-cells 3|tat-interacting protein of 110 kDa
Swissprots	Q2M2H0 A8K2E4 Q96J95 Q8IUS1 Q15020 Q58F06 B7ZKM0
Accessions	EAW97816 EAW97817 Q15020 AB020880 BAA78384 AB073647 AF387506 AAK69347 AI656011 AK225174 AK290209 BAF82898 AK299250 BAG61281 AK302332 BAG63664 AK304834 BAG65578 BC004547 BC015627 BC024279 BC032601 AAH32601 BC041638 AAH41638 BC093784 AAH93784 BC103706 AAI03707 BC111983 AAI11984 BC143253 AAI43254 BQ231651 CN349201 CR933631 D63879 BAA09929 DA391623 XM_005269241 XP_005269298 XM_011539026 XP_011537328 NM_014706 NP_055521
Function	U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). Ma
Subcellular Location	Nucleus, nucleoplasm {ECO:0000269|PubMed:10463607, ECO:0000269|PubMed:11959860, ECO:0000269|PubMed:12578909}. Nucleus, Cajal body {ECO:0000269|PubMed:12578909}. Nucleus speckle {ECO:0000269|PubMed:11959860}. Cytoplasm {ECO:0000269|PubMed:10463607, ECO:0000269|PubMed:11959860}.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:11959860}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SART3 full length protein - ab132420 from Abcam Category Protein Source Wheat germ Species Human

Human SART3 peptide - ab45492 from Abcam Category Peptide Species Human

SART3 Antibody Blocking Peptide - LS-E12153 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SART3 Antibody Blocking Peptide - LS-E14110 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SART3 Antibody Blocking Peptide - LS-E14111 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SART3 Protein - H00009733-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SART3 blocking peptide - GTX89518-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Human SART3 protein - orb246563 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human SART3 protein - orb246856 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SART3 Peptide - AC21-0296-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SART3 / TIP110 - H00009733-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SART3 / TIP110 - H00009733-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SART3 Peptide - 46-338P from ProSci Category Peptide Species Human

SART3 fusion protein - ag12590 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SART3 fusion protein - Ag13277 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3(SART3) - CSB-YP624010HU CSB-BP624010HU CSB-MP624010HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3(SART3) ,partial - CSB-EP624010HU from Cusabio Category Protein Source Yeast Species Human

SART3 / TIP110 - TP310837 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

p100, Recombinant Protein - MBS144788 from MyBioSource Category Protein Prices $140.00, $205.00, $3,515.00 Sizes 5 µg, 20 µg, 1 mg Source Sf9 Insect Cells

SART3, Peptide - MBS425793 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

SART3 Protein - NBP2-13281PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SART3 Peptide, Human - M34GP13792H from Creative Peptides Category Peptide Source Synthetic. Species Human

SART3 Recombinant Protein (OPCA02266) - OPCA02266 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

SART3 Recombinant Protein (OPCA03013) - OPCA03013 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Squamous cell carcinoma antigen recognized by T-cells 3 - AP71299 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

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